Evidence map›Paper›PMID 31395663›Full record

ArticleAJNR. American journal of neuroradiology2019

Analysis of Flow Dynamics and Outcomes of Cerebral Aneurysms Treated with Intrasaccular Flow-Diverting Devices.

J R Cebral, B J Chung, F Mut, J Chudyk, C Bleise, E Scrivano, P Lylyk, R Kadirvel, D Kallmes

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Usefulness of silent magnetic resonance angiography for intracranial aneurysms treated with a flow re-direction endoluminal device.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  2. Geometry of intracranial aneurysms and of intrasaccular devices may influence aneurysmal occlusion rates after endovascular treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Heterogeneous model to evaluate CFD in intracranial bifurcation aneurysms treated with the WEB device to predict angiographic outcome.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J R CebralFrom the Bioengineering Department (J.R.C., F.M.), Volgenau School of Engineering, George Mason University, Fairfax, Virginia jcebral@gmu.edu.ORCID 0000-0002-3216-0856
B J ChungDepartment of Mathematical Sciences (B.J.C.), Montclair State University, Montclair, New Jersey.ORCID 0000-0002-5846-7644
F MutFrom the Bioengineering Department (J.R.C., F.M.), Volgenau School of Engineering, George Mason University, Fairfax, Virginia.ORCID 0000-0003-1907-3739
J ChudykDepartment of Interventional Neuroradiology (J.C., C.B., E.S., P.L.), Clinica ENERI, Buenos Aires, Argentina.ORCID 0000-0003-2551-5169
C BleiseDepartment of Interventional Neuroradiology (J.C., C.B., E.S., P.L.), Clinica ENERI, Buenos Aires, Argentina.ORCID 0000-0003-2292-3263
E ScrivanoDepartment of Interventional Neuroradiology (J.C., C.B., E.S., P.L.), Clinica ENERI, Buenos Aires, Argentina.ORCID 0000-0001-8824-9545
P LylykDepartment of Interventional Neuroradiology (J.C., C.B., E.S., P.L.), Clinica ENERI, Buenos Aires, Argentina.ORCID 0000-0001-7044-4369
R KadirvelDepartment of Interventional Neuroradiology (R.K., D.K.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-6786-9953
D KallmesDepartment of Interventional Neuroradiology (R.K., D.K.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-8495-0040

Funding

Computational and Biological Approach to Flow DiversionR01NS076491 · NINDS · MAYO CLINIC ROCHESTER · PI Juan R Cebral, DAVID F KALLMES · 2011 to 2026
$7.4M
NINDS NIH HHS R01 NS076491
6 · The paper itself

Abstract

background and purposeIntrasaccular flow diversion offers a promising treatment option for complex bifurcation aneurysms. The purpose of this study was to compare the flow conditions between successfully occluded and incompletely occluded aneurysms treated with intrasaccular devices. MATERIALS AND

methodsThe hemodynamics in 18 completely occluded aneurysms after treatment with intrasaccular devices was compared against 18 that were incompletely occluded at follow-up. Hemodynamic and geometric parameters were obtained from computational fluid dynamics models constructed from 3D angiographies. Models of the intrasaccular devices were created and interactively deployed within the vascular models using posttreatment angiography images for guidance. Hemodynamic and geometric variables were compared using the Mann-Whitney test and univariate logistic regression analysis.

resultsIncomplete occlusion was associated with large posttreatment mean aneurysm inflows (

conclusionsThe outcome of cerebral aneurysm treatment with intrasaccular flow diverters is associated with flow conditions created immediately after device implantation. Flow conditions unfavorable for immediate and complete occlusion seem to be created by improper positioning or orientation of the device. Complete occlusion is more difficult to achieve in larger aneurysms, aneurysms with wider necks, and aneurysms with stronger and more complex flows.

Indexed as

Neurosurgical ProceduresVascular Surgical ProceduresAgedBlood Vessel ProsthesisFemaleHemodynamicsHumansHydrodynamicsIntracranial AneurysmMaleMiddle AgedStentsTreatment Outcome

Identifiers

PMID31395663
PMCPMC6732779

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.