Evidence map›Paper›PMID 31395655›Full record

ArticleThe Journal of biological chemistry2019

Deleted in azoospermia-associated protein 2 regulates innate immunity by stimulating Hippo signaling in crab.

Lei Yang, Xuejie Li, Xiang Qin, Qiying Wang, Kaimin Zhou, Hao Li, Xin Zhang, Qun Wang, Weiwei Li

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Immune function analysis ofFrontiers in physiology · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lei YangState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.
Xuejie LiCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Xiang QinState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.
Qiying WangState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.
Kaimin ZhouState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.
Hao LiState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.
Xin ZhangLaboratory of Cellular Immunity, Shuguang Hospital, affiliated with Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China zhangxin68619@163.com.
Qun WangState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China qwang@bio.ecnu.edu.cn.ORCID 0000-0001-7929-7692
Weiwei LiState Key Laboratory of Estuarine and Coastal Research, Laboratory of Invertebrate Immunological Defense and Reproductive Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China wwli@bio.ecnu.edu.cn.
East China Normal University · CNShanghai University of Traditional Chinese Medicine · CNDalian Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Hippo-signaling pathway plays a critical role in both normal animal physiology and pathogenesis. Because pharmacological interventions targeting this pathway have diverse clinical implications, a better understanding of its regulation in various conditions and organisms is crucial. Here, we identified deleted in azoospermia-associated protein 2 (DAZAP2) in the Chinese mitten crab (

Indexed as

Amino Acid SequenceAnimalsArthropod ProteinsBrachyuraGene Expression RegulationImmunity, InnateJanus KinasesProtein Serine-Threonine KinasesRNA-Binding ProteinsSequence AlignmentSignal TransductionArthropod ProteinsDAZAP1 protein, humanDAZAP2 protein, humanJanus KinasesProtein Serine-Threonine KinasesRNA-Binding ProteinsbacteriaDAZAP2gene transcriptionHippo signalingimmunologyprotein–protein interactionyeast two-hybrid

Identifiers

PMID31395655
PMCPMC6779444
OpenAlexW2968281378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.