Evidence map›Paper›PMID 31395019›Full record

Trial reportBMC infectious diseases2019

Linkage to hepatitis C care after incarceration in jail: a prospective, single arm clinical trial.

Matthew J Akiyama, Devin Columbus, Ross MacDonald, Alison O Jordan, Jessie Schwartz, Alain H Litwin, Benjamin Eckhardt, Ellie Carmody

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04036760 (Implementation and Evaluation of Care Coordination in Linkage to Care for Hepatitis C Following Release From New York City Jails), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04036760 completednot on this map

Implementation and Evaluation of Care Coordination in Linkage to Care for Hepatitis C Following Release From New York City Jails

TypeobservationalSponsorNYU Langone HealthRan2015 to 2017Enrolled105ConditionsHepatitis CArmsResearch transitional care coordination
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Testing and Linkage to Hepatitis C Care From Alternative-to-Incarceration Programs: The Right Place? The Right Time?Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew J AkiyamaMontefiore Medical Center/Albert Einstein College of Medicine, 3300 Kossuth Ave, Bronx, NY, 10467, USA. makiyama@montefiore.org.ORCID http://orcid.org/0000-0003-4290-3083
Devin ColumbusNew York University School of Medicine, New York, NY, USA.
Ross MacDonaldNew York City Health + Hospitals, Correctional Health Services, New York, NY, USA.
Alison O JordanNew York City Health + Hospitals, Correctional Health Services, New York, NY, USA.
Jessie SchwartzNew York City Department of Health and Mental Hygiene, Queens, NY, USA.
Alain H LitwinUniversity of South Carolina School of Medicine, Greenville, South Carolina, USA.
Benjamin EckhardtNew York University School of Medicine, New York, NY, USA.
Ellie CarmodyNew York University School of Medicine, New York, NY, USA.

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Kathryn M. Anastos · 2017 to 2026
$28.3M
Accessible Care Intervention for Engaging People who Inject Illicit Drugs (PWID) in Hepatitis C CareR01DA041298 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MARKS, KRISTEN M, MATEU-GELABERT, PEDRO · 2016 to 2020
$2.8M
Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants Living with Hepatitis C-The HCV-ACCELERATE TrialK99DA043011 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AKIYAMA, MATTHEW · 2017 to 2018
$369k
NIAID NIH HHS P30 AI124414NIDA NIH HHS K99 DA043011NIDA NIH HHS K99DA043011NIDA NIH HHS R01 DA041298
6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) is a major public health problem in correctional settings. HCV treatment is often not possible in U.S. jails due to short lengths of stay. Linkage to care is crucial in these settings, but competing priorities complicate community healthcare engagement and retention after incarceration.

methodsWe conducted a single arm clinical trial of a combined transitional care coordination (TCC) and patient navigation intervention and assessed the linkage rate and factors associated with linkage to HCV care after incarceration.

resultsDuring the intervention, 84 participants returned to the community after their index incarceration. Most participants were male and Hispanic, with a history of mental illness and a mean age of 45 years. Of those who returned to the community, 26 (31%) linked to HCV care within a median of 20.5 days; 17 (20%) initiated HCV treatment, 15 (18%) completed treatment, 9 (11%) had a follow-up lab drawn to confirm sustained virologic response (SVR), and 7 (8%) had a documented SVR. Among those with follow-up labs the known SVR rate was (7/9) 78%. Expressing a preference to be linked to the participant's existing health system, being on methadone prior to incarceration, and feeling that family or a loved one were concerned about the participant's wellbeing were associated with linkage to HCV care. Reporting drinking alcohol to intoxication prior to incarceration was negatively associated with linkage to HCV care.

conclusionWe demonstrate that an integrated strategy with combined TCC and patient navigation may be effective in achieving timely linkage to HCV care. Additional multicomponent interventions aimed at treatment of substance use disorders and increasing social support could lead to further improvement.

trial registrationClinicaltrials.gov NCT04036760 July 30th, 2019 (retrospectively registered).

Indexed as

Continuity of Patient CareAdultCommunity Health ServicesFemaleHepatitis CHispanic or LatinoHumansMaleMethadoneMiddle AgedNew YorkPatient NavigationPrisonersPrisonsProspective StudiesSubstance-Related DisordersMethadoneHCVJailLinkage to carePrisonPWID

Identifiers

PMID31395019
PMCPMC6686449

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.