Observational studyBMC anesthesiology2019
Emergence delirium in children is not related to intraoperative burst suppression - prospective, observational electrography study.
Observational study in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02481999 (Pre- and Postoperative EEG-Monitoring for Children Aged From 0,5 to 8 Years), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pre- and Postoperative EEG-Monitoring for Children Aged From 0,5 to 8 Years
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Risk factors and incidence of postoperative delirium after cardiac surgery in children: a systematic review and meta-analysis.Italian journal of pediatrics · 2024Pooled it
- Age-specific electroencephalography dynamics during anesthesia: monitoring and neurocognitive implications.Anesthesia and pain medicine · 2025Review
- Laparotomy and burst suppression-inducing sevoflurane induce subtle long-term changes in anxiety and social behavior in late postnatal mice.Korean journal of anesthesiology · 2025Article
- EEG-Guided Titration of Sevoflurane and Pediatric Anesthesia Emergence Delirium: A Randomized Clinical Trial.JAMA pediatrics · 2025Article
- Impact of Intraoperative Blood Transfusion on Cerebral Injury in Pediatric Patients Undergoing Congenital Septal Heart Defect Surgery.Journal of clinical medicine · 2024Article
- Emergence delirium: an overview with an emphasis on the use of electroencephalography in its management.Anesthesia and pain medicine · 2024Article
- Intraoperative pediatric electroencephalography monitoring: an updated review.Korean journal of anesthesiology · 2024Review
- Correlation between burst suppression and postoperative delirium in elderly patients: a prospective study.Aging clinical and experimental research · 2023Article
- Article
- Depth of anesthesia, temperature, and postoperative delirium in children and adolescents undergoing cardiac surgery.BMC anesthesiology · 2023Article
- Desflurane is risk factor for postoperative delirium in older patients' independent from intraoperative burst suppression duration.Frontiers in aging neuroscience · 2023Article
- A retrospective study of electroencephalography burst suppression in children undergoing general anesthesia.Pediatric investigation · 2021Article
- Electroencephalographic assessment of infant spinal anesthesia: A pilot prospective observational study.Paediatric anaesthesia · 2021Observational
- Impact of Propofol Bolus Administration on the Nociceptive Flexion Reflex Threshold and Bispectral Index in Children-A Case Series.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmergence-delirium is the most frequent brain dysfunction in children recovering from general anaesthesia, though the pathophysiological background remains unclear. The presented study analysed an association between emergence delirium and intraoperative Burst Suppression activity in the electroencephalogram, a period of very deep hypnosis during general anaesthesia.
methodsIn this prospective, observational cohort study at the Charité - university hospital in Berlin / Germany children aged 0.5 to 8 years, undergoing planned surgery, were included between September 2015 and February 2017. Intraoperative bi-frontal electroencephalograms were recorded. Occurrence and duration of Burst Suppression periods were visually analysed. Emergence delirium was assessed using the Pediatric Assessment of Emergence Delirium Score.
resultsFrom 97 children being analysed within this study, 40 children developed emergence delirium, and 57 children did not. Overall 52% of the children displayed intraoperative Burst Suppression periods; however, occurrence and duration of Burst Suppression (Emergence delirium group 55% / 261 + 462 s vs. Non-emergence delirium group 49% / 318 + 531 s) did not differ significantly between both groups.
conclusionsOur data reveal no correlation between the occurrence and duration of intraoperative Burst Suppression activity and the incidence of emergence delirium. Burst Suppression occurrence is frequent; however, it does not seem to have an unfavourable impact on cerebral function at emergence from general anaesthesia in children. TRAIL REGISTRATION: NCT02481999, June 25, 2015.
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