ArticleThe Journal of neuropsychiatry and clinical neurosciences2020
Characterizing the Link Between Glial Activation and Changed Functional Connectivity in National Football League Players Using Multimodal Neuroimaging.
Article in The Journal of neuropsychiatry and clinical neurosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Repeat traumatic brain injury exacerbates acute thalamic hyperconnectivity in humans.Brain communications · 2024Article
- Article
- Have (R)-[European journal of nuclear medicine and molecular imaging · 2021Article
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe primary objective of this preliminary study was to examine the impact of NFL play on interregional functional connectivity between two brain regions, the supramarginal gyrus (SMG) and the thalamus, identified as having higher binding of [
methodsResting-state functional MRI was used to examine functional brain changes between regions with evidence of past injury in active or recently retired NFL players (defined as ≤12 years since NFL play) and distantly retired players (defined as >12 years since NFL play). Age-comparable individuals without a history of concussion or participation in collegiate or professional collision sports were included as a control group.
resultsCompared with healthy control subjects, NFL players showed a loss of anticorrelation between the left SMG and bilateral thalami (mean z score=-2.434, p=0.015). No difference was observed when examining right SMG connectivity. The pattern of connectivity in active and recently retired players mimicked the pattern observed in distantly retired players and older control subjects.
conclusionsFurther study of the clinical significance of this altered pattern of interregional connectivity in active and recently retired NFL players is needed.
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