Evidence map›Paper›PMID 31394960›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Calibrated fMRI for dynamic mapping of CMRO

Erin K Englund, Maria A Fernández-Seara, Ana E Rodríguez-Soto, Hyunyeol Lee, Zachary B Rodgers, Marta Vidorreta, John A Detre, Felix W Wehrli

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  6. Validation of a new 3D quantitative BOLD based cerebral oxygen extraction mapping.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  7. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  8. Review
  9. Review
  10. Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  11. Article
  12. Challenges and opportunities of mesoscopic brain mapping with fMRI.Current opinion in behavioral sciences · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Erin K EnglundLaboratory for Structural, Physiologic and Functional Imaging (LSPFI), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-0231-1289
Maria A Fernández-SearaDepartment of Radiology, Clínica Universidad de Navarra, Pamplona, Spain.
Ana E Rodríguez-SotoLaboratory for Structural, Physiologic and Functional Imaging (LSPFI), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Hyunyeol LeeLaboratory for Structural, Physiologic and Functional Imaging (LSPFI), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Zachary B RodgersLaboratory for Structural, Physiologic and Functional Imaging (LSPFI), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Marta VidorretaDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
John A DetreDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Felix W WehrliLaboratory for Structural, Physiologic and Functional Imaging (LSPFI), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · USClinica Universidad de Navarra · ESSiemens (Spain) · ES

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
Dynamic MRI Mapping of CMRO2 ResponsesR21EB022687 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2017 to 2018
$443k
NIBIB NIH HHS P41 EB015893NIBIB NIH HHS R21 EB022687NIBIB NIH HHS T32 EB020087
6 · The paper itself

Abstract

Functional MRI (fMRI) can identify active foci in response to stimuli through BOLD signal fluctuations, which represent a complex interplay between blood flow and cerebral metabolic rate of oxygen (CMRO

Indexed as

AdultBrainCalibrationCerebrovascular CirculationFemaleGray MatterHumansHypercapniaHyperoxiaMagnetic Resonance ImagingMaleOxygenOxygen ConsumptionSpin LabelsOxygenSpin LabelsArterial spin labelingBOLDcalibrated fMRIcerebral metabolic rate of oxygenmagnetic resonance imaging

Identifiers

PMID31394960
PMCPMC7308517
OpenAlexW2968668398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.