Evidence map›Paper›PMID 31394887›Full record

ArticleDiagnostics (Basel, Switzerland)2019

Evaluation of Malignancy Risk in 18F-FDG PET/CT Thyroid Incidentalomas.

Maria-Iulia Larg, Dragoș Apostu, Claudiu Peștean, Katalin Gabora, Iulian Claudiu Bădulescu, Elena Olariu, Doina Piciu

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Focal Thyroid Incidentalomas onFrontiers in endocrinology · 2021
    Pooled it
  2. Article
  3. Definitions of Incidental [Diagnostics (Basel, Switzerland) · 2024
    Review
  4. Review
  5. Radiomics Analysis of [Diagnostics (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria-Iulia LargProf. Dr. Ion Chiricuță Institute of Oncology, Department of Nuclear Medicine, 400015 Cluj-Napoca, Romania. mariaiulia.larg@yahoo.com.
Dragoș ApostuFaculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Claudiu PeșteanProf. Dr. Ion Chiricuță Institute of Oncology, Department of Nuclear Medicine, 400015 Cluj-Napoca, Romania.
Katalin GaboraProf. Dr. Ion Chiricuță Institute of Oncology, Department of Nuclear Medicine, 400015 Cluj-Napoca, Romania.
Iulian Claudiu BădulescuFaculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Elena OlariuProf. Dr. Ion Chiricuță Institute of Oncology, Department of Nuclear Medicine, 400015 Cluj-Napoca, Romania.
Doina PiciuProf. Dr. Ion Chiricuță Institute of Oncology, Department of Nuclear Medicine, 400015 Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid incidentalomas detected by 18 fluoro-2-deoxy-d-glucose (FDG)-positron emission tomography/computed tomography (PET/CT) are a real challenge for nuclear medicine physicians and clinicians. This study aimed to evaluate the risk of malignancy for patients with focal thyroid incidentalomas (TIs) diagnosed through FDG PET/CT. Data from 6900 patients, with a known primary tumor, who had an FDG PET/CT investigation performed were analyzed for the presence of incidental thyroid uptake. The focal TIs were reported, and the patients were referred for further investigation to the endocrinology department. There were 126 patients (1.82%) who presented with focal thyroid uptake, and for 87 of them, investigations were completed with ultrasonography (US), and for 29 with a fine needle aspiration biopsy (FNAB) procedure. Malignancy was detected in 7.93% (10/126) of cases. An arbitrary cutoff value of four was established for the standard uptake value lean body mass (SUVlbm Max) to differentiate the malignant nodules from the benign ones, and this value was significantly associated with malignancy (

Indexed as

FDG PET/CTmalignancy riskthyroid incidentalomas

Identifiers

PMID31394887
PMCPMC6787921

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.