ArticleLife (Basel, Switzerland)2019
Survival of RNA Replicators is much Easier in Protocells than in Surface-Based, Spatial Systems.
Article in Life (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Conditions Enabling the Persistence of Cooperating Synthetase, Ligase, and Mutation-Inhibitor Catalytic Polymers.Journal of molecular evolution · 2026Article
- Biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks: degenerating parasite-specific hyperparasite catalysts confer parasite resistance and herald the birth of molecular immunity.PLoS computational biology · 2025Article
- Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems.Npj complexity · 2025Article
- Evolution of Cellular Organization Along the First Branches of the Tree of Life.Journal of molecular evolution · 2024Article
- Protocell Effects on RNA Folding, Function, and Evolution.Accounts of chemical research · 2024Article
- RNA life on the edge of catastrophe.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The RNA-DNA world and the emergence of DNA-encoded heritable traits.RNA biology · 2024Article
- Coevolution of reproducers and replicators at the origin of life and the conditions for the origin of genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- How did life become cellular?Proceedings. Biological sciences · 2023Article
- Rolling Circles as a Means of Encoding Genes in the RNA World.Life (Basel, Switzerland) · 2022Article
- The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity.Life (Basel, Switzerland) · 2022Article
- RNA World Modeling: A Comparison of Two Complementary Approaches.Entropy (Basel, Switzerland) · 2022Article
- Genome Evolution from Random Ligation of RNAs of Autocatalytic Sets.International journal of molecular sciences · 2021Article
- Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world.Proceedings. Biological sciences · 2021Article
- The Origin(s) of Cell(s): Pre-Darwinian Evolution from FUCAs to LUCA : To Carl Woese (1928-2012), for his Conceptual Breakthrough of Cellular Evolution.Journal of molecular evolution · 2021Article
- Primitive Compartmentalization for the Sustainable Replication of Genetic Molecules.Life (Basel, Switzerland) · 2021Review
- The requirement of cellularity for abiogenesis.Computational and structural biotechnology journal · 2021Review
- Thresholds in Origin of Life Scenarios.iScience · 2020Review
- Origin of Life: The Point of No Return.Life (Basel, Switzerland) · 2020Article
- The Coevolution of Cellularity and Metabolism Following the Origin of Life.Journal of molecular evolution · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the system by parasites: spatial clustering in models with limited diffusion, or group selection in protocells. Here, we compare computational models of replication in spatial models and protocells as closely as possible in order to determine the relative importance of these mechanisms in the RNA World. For the survival of the polymerases, the replication rate must be greater than a minimum threshold value,
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