Evidence map›Paper›PMID 31394799›Full record

ReviewMolecules (Basel, Switzerland)2019

A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [

Cyril Fersing, Ahlem Bouhlel, Christophe Cantelli, Philippe Garrigue, Vincent Lisowski, Benjamin Guillet

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Comparison of twoEJNMMI radiopharmacy and chemistry · 2026
    Article
  3. cGMP-compliant high-yield automated production of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  4. The [18F] F-PSMA Probe: Chemical Perspectives.Current medicinal chemistry · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. One-Step Synthesis of [ACS central science · 2024
    Article
  10. Article
  11. SyntheticRSC medicinal chemistry · 2024
    Review
  12. Review
  13. Review
  14. Evaluation of [Pharmaceutics · 2023
    Article
  15. Article
  16. [Frontiers in oncology · 2023
    Article
  17. Review
  18. Review
  19. Translating a radiolabeled imaging agent to the clinic.Advanced drug delivery reviews · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cyril FersingInstitut de Recherche en Cancérologie de Montpellier (IRCM), University of Montpellier, INSERM U1194, Montpellier Cancer Institute (ICM), 34298 Montpellier, France. cyril.fersing@icm.unicancer.fr.ORCID 0000-0002-4455-4641
Ahlem BouhlelCERIMED, Aix-Marseille University, 13005 Marseille, France.
Christophe CantelliInstitut de Recherche en Cancérologie de Montpellier (IRCM), University of Montpellier, INSERM U1194, Montpellier Cancer Institute (ICM), 34298 Montpellier, France.
Philippe GarrigueCERIMED, Aix-Marseille University, 13005 Marseille, France.ORCID 0000-0002-5712-2055
Vincent LisowskiInstitut des Biomolécules Max Mousseron, UMR 5247, CNRS, Université de Montpellier, ENSCM, UFR des Sciences Pharmaceutiques et Biologiques, 34093 Montpellier CEDEX, France.
Benjamin GuilletCERIMED, Aix-Marseille University, 13005 Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron emission tomography (PET) imaging, for both preclinical and clinical applications. However, usual biomolecules radiofluorination procedures require the formation of covalent bonds with fluorinated prosthetic groups. This drawback makes radiofluorination impractical for routine radiolabeling, gallium-68 appearing to be much more convenient for the labeling of chelator-bearing PET probes. In response to this limitation, a recent expansion of the

Indexed as

Chelating AgentsIsotope LabelingAluminumAnimalsBiomarkersFluorine CompoundsFluorine RadioisotopesGallium RadioisotopesHumansMolecular ImagingMolecular StructurePeptidesPositron-Emission TomographyProtein ConformationAluminumBiomarkersChelating AgentsFluorine-18Fluorine CompoundsFluorine RadioisotopesGallium-68Gallium RadioisotopesPeptidesaluminum fluoridebifunctional chelating agentcoordination chemistrymolecular imagingNOTAPETradiofluorination

Identifiers

PMID31394799
PMCPMC6719958

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.