Evidence map›Paper›PMID 31394791›Full record

ReviewJournal of clinical medicine2019

Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit.

Micheal Strein, John P Holton-Burke, LaTangela R Smith, Gretchen M Brophy

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Brain development in newborns and infants after ECMO.World journal of pediatrics : WJP · 2024
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Seizures and Sepsis: A Narrative Review.Journal of clinical medicine · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Micheal StreinDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA 23298-0533, USA.
John P Holton-BurkeDepartment of Neurology, Virginia Commonwealth University Health System, Richmond, VA 23298-0599, USA.
LaTangela R SmithDepartment of Neurology, Virginia Commonwealth University Health System, Richmond, VA 23298-0599, USA.
Gretchen M BrophyDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA 23298-0533, USA. gbrophy@vcu.edu.ORCID 0000-0002-4749-2693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing no overt clinical signs of seizures. Outcomes in patients with unidentified seizure activity tend to be poor, and mortality significantly increases in those who have seizure activity longer than 30 min. Prompt diagnosis and provision of medical therapy are crucial in order to attain successful seizure termination and prevent poor outcomes. In this article, we review the epidemiology and pathophysiology of seizures in the critically ill, various seizure monitoring modalities, and recommended medical therapy.

Indexed as

antiepileptic therapycritical careelectroencephalographyneurocritical careseizuresstatus epilepticus

Identifiers

PMID31394791
PMCPMC6722541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.