Evidence map›Paper›PMID 31394732›Full record

ReviewMolecules (Basel, Switzerland)2019

Gingers and Their Purified Components as Cancer Chemopreventative Agents.

John F Lechner, Gary D Stoner

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

  1. Local Delivery of Ginger ExtractCurrent drug delivery · 2026
    Article
  2. Design and Evaluation of aPharmaceutics · 2025
    Article
  3. Article
  4. Review
  5. Anticancer Properties of Garlic and Ginger Extract in Colon Cancer Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The Management of Diabetes Mellitus Using Medicinal Plants and Vitamins.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

John F LechnerRetired from Department of Medicine, Division of Medical Oncology, Ohio State University, Columbus 43210, OH, USA. johnf.lechner@gmail.com.ORCID 0000-0003-0044-7593
Gary D StonerDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.
Montana State University · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemoprevention by ingested substituents is the process through which nutraceuticals and/or their bioactive components antagonize carcinogenesis. Carcinogenesis is the course of action whereby a normal cell is transformed into a neoplastic cell. This latter action involves several steps, starting with initiation and followed by promotion and progression. Driving these stages is continued oxidative stress and inflammation, which in turn, causes a myriad of aberrant gene expressions and mutations within the transforming cell population and abnormal gene expressions by the cells within the surrounding lesion. Chemoprevention of cancer with bioreactive foods or their extracted/purified components occurs primarily via normalizing these inappropriate gene activities. Various foods/agents have been shown to affect different gene expressions. In this review, we discuss how the chemoprevention activities of gingers antagonize cancer development.

Indexed as

AnimalsAnticarcinogenic AgentsChemopreventionHumansPlant ExtractsStructure-Activity RelationshipZingiber officinaleAnticarcinogenic AgentsPlant Extractsapoptosiscancer chemopreventiongingerolsparadolsshogaolszerumbonezingerone

Identifiers

PMID31394732
PMCPMC6719158
OpenAlexW2966787352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.