Evidence map›Paper›PMID 31394729›Full record

ArticleCancers2019

Novel Strategies for Cancer Treatment: Highlights from the 55th IACR Annual Conference.

Sara Charmsaz, Denis M Collins, Antoinette S Perry, Maria Prencipe

Abstract readConference Proceedings
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Design, Synthesis, Biological andCurrent computer-aided drug design · 2025
    Article
  9. Article
  10. Review
  11. Cytotoxic Effects of Ardisiacrispin A fromLife (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Review
  14. Challenges and new technologies in adoptive cell therapy.Journal of hematology & oncology · 2023
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara CharmsazEndocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, D2 Dublin, Ireland.ORCID 0000-0002-6003-702X
Denis M CollinsNational Institute for Cellular Biotechnology, Dublin City University, Glasnevin, D9 Dublin, Ireland.
Antoinette S PerryCancer Biology and Therapeutics Laboratory, UCD Conway Institute, University College Dublin, Belfield, D4 Dublin, Ireland.ORCID 0000-0002-6108-512X
Maria PrencipeCancer Biology and Therapeutics Laboratory, UCD Conway Institute, University College Dublin, Belfield, D4 Dublin, Ireland. maria.prencipe@ucd.ie.ORCID 0000-0002-8864-1560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While conventional cancer treatments, such as surgery, radiotherapy and chemotherapy, have been combined for decades in an effort to treat cancer patients, the emergence of novel fields of cancer research have led to a renewed interest in combining conventional treatments with more innovative approaches. The realisation that cancer progression is not exclusively due to changes in the cancer epithelial cells, but also involves changes in the tumour microenvironment, has opened new avenues for combination treatments. Here we discuss the use of combination therapies presented at the 55th Irish Association for Cancer Research (IACR) Annual Conference, highlighting examples of novel therapeutic strategies which, combined with conventional therapies, may greatly enhance not only the overall outcome for patients, but also the quality of life for cancer survivors. Among the novel treatment strategies, immune metabolism, epigenetic therapies and physical exercise are presented. In addition, novel technologies in the field of precision medicine, which will be useful to discover new therapeutics and to stratify patients for combination treatments, are also discussed.

Indexed as

cancer therapeuticscombination therapyepigeneticsimmune therapyliquid biopsiesmulti-omicsphysical exercise

Identifiers

PMID31394729
PMCPMC6721818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.