Evidence map›Paper›PMID 31394408›Full record

ArticleVirology2019

Isoform specific editing of the coxsackievirus and adenovirus receptor.

James M Readler, Amal S AlKahlout, Priyanka Sharma, Katherine J D A Excoffon

Open access · greenAbstract read
In one paragraph

Article in Virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Human adenovirus serotype 5 infection dysregulates cysteine, purine, and unsaturated fatty acid metabolism in fibroblasts.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Article
  5. Canine Adenovirus 1 Isolation Bioinformatics Analysis of the Fiber.Frontiers in cellular and infection microbiology · 2022
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James M ReadlerBiomedical Sciences PhD Program, Wright State University, Dayton, OH, 45435, USA; Boonshoft School of Medicine, Wright State University, Dayton, OH, 45435, USA.
Amal S AlKahloutDepartment of Biological Sciences, Wright State University, Dayton, OH, 45435, USA.
Priyanka SharmaDepartment of Biological Sciences, Wright State University, Dayton, OH, 45435, USA.
Katherine J D A ExcoffonBiomedical Sciences PhD Program, Wright State University, Dayton, OH, 45435, USA; Boonshoft School of Medicine, Wright State University, Dayton, OH, 45435, USA; Department of Biological Sciences, Wright State University, Dayton, OH, 45435, USA. Electronic address: katherine.excoffon@wright.edu.
Wright State University · US

Funding

Prevention of adenovirus pathogenesis through downregulation of the apical adenovirus receptorR01AI127816 · NIAID · WRIGHT STATE UNIVERSITY · PI KOLAWOLE, ABIMBOLA OLAYINKA · 2017 to 2021
$1.9M
Isoform-specific Regulation of the Coxsackie and Adenovirus Receptor in Polarized EpitheliaR15AI090625 · NIAID · WRIGHT STATE UNIVERSITY · PI EXCOFFON, KATHERINE JULIE · 2010 to 2015
$881k
NIAID NIH HHS R01 AI127816NIAID NIH HHS R15 AI090625
6 · The paper itself

Abstract

The Coxsackievirus and adenovirus receptor (CAR) is both a viral receptor and cell adhesion protein. CAR has two transmembrane isoforms that localize distinctly in polarized epithelial cells. Whereas the seven exon-encoded isoform (CAR

Indexed as

CRISPR-Cas SystemsGene Expression Regulation, ViralAdenoviruses, HumanAnimalsBase SequenceClustered Regularly Interspaced Short Palindromic RepeatsCoxsackie and Adenovirus Receptor-Like Membrane ProteinCRISPR-Associated Protein 9DNA, ComplementaryDogsDoxycyclineExonsGene EditingHumansMadin Darby Canine Kidney CellsPromoter Regions, GeneticCoxsackie and Adenovirus Receptor-Like Membrane ProteinCRISPR-Associated Protein 9DNA, ComplementaryDoxycyclineProtein IsoformsRNA, Guide, CRISPR-Cas SystemsAdenovirusApical and basolateralCoxsackievirus and adenovirus receptor (CAR)CRISPR/Cas9 and single guide RNA (sgRNA)Polarized epithelia

Identifiers

PMID31394408
PMCPMC6733617
OpenAlexW2964848800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.