Evidence map›Paper›PMID 31393367›Full record

SynthesisMedicine2019

Is low body mass index a risk factor for semen quality? A PRISMA-compliant meta-analysis.

Dan Guo, Min Xu, Qifan Zhou, Chunhua Wu, Rong Ju, Jiazhen Dai

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dan GuoDepartment of Preventive Health Branch, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing.
Min XuReproductive Health and Infertility Clinic, Huai'an First People's Hospital, Nanjing Medical University, Huai'an.
Qifan ZhouDepartment of Preventive Health Branch, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing.
Chunhua WuDepartment of Preventive Health Branch, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing.
Rong JuDepartment of Gynaecology and Obstetrics, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, China.
Jiazhen DaiDepartment of Preventive Health Branch, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMale infertility has become a worldwide public health problem. However, the effect of low body mass index (BMI) is still controversial.

methodsRelevant articles in Pubmed, Embase, Web of science, and Wanfang database published until September 2017 were searched without language restriction. We performed a meta-analysis about low BMI and semen parameters containing total sperm count, concentration, semen volume, and sperm motility (overall and progressive), including 709 men with low BMI and 14,622 men with normal BMI.

resultsThirteen studies were included in this meta-analysis and a total of 15,331 individuals were accumulated. We pooled data from these articles and found standardized weighted mean differences in semen parameters (total sperm count and semen volume) showed significant difference between low BMI and normal BMI.

conclusionsThis systematic review with meta-analysis has confirmed that there was a relationship between low BMI and semen quality, which suggesting low BMI may be a harmful factor of male infertility. Yet lacking of the raw data may influence the accuracy of the results. Further researches are needed to identify the role of underweight in male sterility.

Indexed as

Body Mass IndexCase-Control StudiesHumansInfertility, MaleMaleRisk FactorsSperm CountSperm MotilityThinness

Identifiers

PMID31393367
PMCPMC6709190

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.