Observational studyCritical care medicine2019
Emergency Department to ICU Time Is Associated With Hospital Mortality: A Registry Analysis of 14,788 Patients From Six University Hospitals in The Netherlands.
Observational study in Critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Critical care delivery models in emergency departments: a systematic review of the literature and meta-analysis of related outcome effects.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Pooled it
- Enhancing Care for Critically Ill Patients Boarding in the Emergency Department: A 360° Evaluation of an Emergency Medicine Critical Care Fellow Model.Journal of the American College of Emergency Physicians open · 2026Article
- Delayed at the Door: Impact of Pandemic Response Policies on Emergency and Critical Care in Korea: An Interrupted Time-Series Analysis.Journal of Korean medical science · 2026Article
- Determinants of Emergency Department Length of Stay and the Mediation Effect of Disposition Among Injury Patients in South Korea: A Nationwide Retrospective Study.Healthcare (Basel, Switzerland) · 2026Article
- Lung Ultrasound Offers Fast and Reliable Exclusion of Heart Failure in the Emergency Department: A Prospective Diagnostic Study.Diagnostics (Basel, Switzerland) · 2025Article
- Initial management and outcome of community-acquired bacterial meningitis in two French ICUs over a period of fifteen years.BMC infectious diseases · 2025Observational
- Association between emergency department-to-intensive care unit transfer time and mortality in patients with septic shock: a target trial emulation with septic shock in South Korea.Acute and critical care · 2025Article
- The 6-hour window: is the sepsis transfer guideline enough?Acute and critical care · 2025Article
- The Diabetic-Thyroid Link: A Cross-Sectional Study of Thyroid Dysfunction Prevalence in a Diabetic Population.Cureus · 2025Article
- ICU admission delays: Impact on length of stay and long-term outcomes.Biomolecules & biomedicine · 2025Article
- Shortening emergency department length of stay: Fast track, short-stay unit and acute medical unit.Exploratory research in clinical and social pharmacy · 2025Review
- Predictors of Mortality in Medical ICU Patients: A Retrospective Study in a Tertiary Care Center in Jordan.Journal of clinical medicine · 2025Article
- Association between emergency department to intensive care units time and in-hospital mortality: an analysis of the MIMIC-IV database.BMJ open · 2025Observational
- Rapid non-invasive measurement of mitochondrial oxygen tension after microneedle pre-treatment: a feasibility study in human volunteers.Journal of clinical monitoring and computing · 2025Article
- Predictive and Prognostic Importance of National Early Warning Score 2 (NEWS2) in Emergency Room Patients.Cureus · 2025Article
- Mortality and Length of Stay Implications of Deterioration-Associated Transfer to the Intensive Care Unit over Different Time Frames.Health services insights · 2025Article
- Rearranging the furniture: A blueprint for reappropriating fixed resources to create an emergency department resuscitative care unit.Journal of the American College of Emergency Physicians open · 2024Article
- Impact of the early phase of the COVID-19 pandemic on emergency department-to-intensive care unit admissions in Korea: an interrupted time-series analysis.BMC emergency medicine · 2024Article
- Long-term, patient-centered, frailty-based outcomes of older critical illness survivors from the emergency department: a post hoc analysis of the LIFE Study.BMC geriatrics · 2024Observational
- Quality Improvement Curriculum for Intensive Care Unit Upgrades.The western journal of emergency medicine · 2023Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesProlonged emergency department to ICU waiting time may delay intensive care treatment, which could negatively affect patient outcomes. The aim of this study was to investigate whether emergency department to ICU time is associated with hospital mortality. DESIGN, SETTING, AND PATIENTS: We conducted a retrospective observational cohort study using data from the Dutch quality registry National Intensive Care Evaluation. Adult patients admitted to the ICU directly from the emergency department in six university hospitals, between 2009 and 2016, were included. Using a logistic regression model, we investigated the crude and adjusted (for disease severity; Acute Physiology and Chronic Health Evaluation IV probability) odds ratios of emergency department to ICU time on mortality. In addition, we assessed whether the Acute Physiology and Chronic Health Evaluation IV probability modified the effect of emergency department to ICU time on mortality. Secondary outcomes were ICU, 30-day, and 90-day mortality.
interventionsNone. MEASUREMENTS AND MAIN
resultsA total of 14,788 patients were included. The median emergency department to ICU time was 2.0 hours (interquartile range, 1.3-3.3 hr). Emergency department to ICU time was correlated to adjusted hospital mortality (p < 0.002), in particular in patients with the highest Acute Physiology and Chronic Health Evaluation IV probability and long emergency department to ICU time quintiles: odds ratio, 1.29; 95% CI, 1.02-1.64 (2.4-3.7 hr) and odds ratio, 1.54; 95% CI, 1.11-2.14 (> 3.7 hr), both compared with the reference category (< 1.2 hr). For 30-day and 90-day mortality, we found similar results. However, emergency department to ICU time was not correlated to adjusted ICU mortality (p = 0.20).
conclusionsProlonged emergency department to ICU time (> 2.4 hr) is associated with increased hospital mortality after ICU admission, mainly driven by patients who had a higher Acute Physiology and Chronic Health Evaluation IV probability. We hereby provide evidence that rapid admission of the most critically ill patients to the ICU might reduce hospital mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.