ArticleEuropean journal of oral sciences2019
Bisphenol A in human saliva and urine before and after treatment with dental polymer-based restorative materials.
Article in European journal of oral sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02575118 (Concentration of Bisphenol A in Saliva and Urine Before and After Treatment With Polymer-based Dental Filling Materials), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Concentration of Bisphenol A in Saliva and Urine Before and After Treatment With Polymer-based Dental Filling Materials
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Toxicity of resin-matrix composites in a dental clinical setting.Odontology · 2025Pooled it
- Exploring saliva as a biofluid for biomonitoring of diet-related contaminants exposure: insights from a literature mining approach.Journal of exposure science & environmental epidemiology · 2026Review
- Bisphenol-A Release from Modern Resin-Based Dental Composites: A Time-Dependent In Vitro Assessment.Polymers · 2026Article
- Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis.Animals : an open access journal from MDPI · 2026Article
- Dental composite-resin materials and oral-systemic health: clinical toxicology insights.Frontiers in public health · 2026Review
- Mechanistic exploration of bisphenol A in primary Sjögren's syndrome using network toxicology, molecular docking, molecular dynamics simulations and experimental validation.BMC pharmacology & toxicology · 2025Article
- Methanolic extract of wheatgrass (3 Biotech · 2024Article
- Monomer Release from Dental Resins: The Current Status on Study Setup, Detection and Quantification for In Vitro Testing.Polymers · 2022Review
- Structural Changes in Resin-Based Composites in Saliva of Patients with Leukemia before Starting Chemotherapeutic Regimen.Polymers · 2022Article
- Bisphenol A Release from Dental Composites and Resin-Modified Glass Ionomers under Two Polymerization Conditions.Polymers · 2021Article
- Bisphenol A Exposure in Exclusively Breastfed Infants and Lactating Women: An Observational Cross-sectional StudyJournal of clinical research in pediatric endocrinology · 2021Observational
- Contrasting prenatal nutrition and environmental exposures in association with birth weight and cognitive function in children at 7 years.BMJ nutrition, prevention & health · 2020Article
- A Prospective Cohort Study of Bisphenol A Exposure from Dental Treatment.Journal of dental research · 2020Article
- Bisphenol A in human saliva and urine before and after treatment with dental polymer-based restorative materials.European journal of oral sciences · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to quantify bisphenol A (BPA) concentrations in saliva and urine before and after treatment with dental polymer-based restorative materials to assess if placement of this material is associated with increased BPA levels in saliva and urine. Twenty individuals in need of at least one dental restoration with polymer-based restorative material were included in this study. The participants were instructed to abstain from eating, drinking, and brushing their teeth for at least 10 h prior to sampling. Saliva and urine were collected before and 10 min (saliva only), 1 h, 24 h, and 1 wk after treatment. Samples were stored at -80°C before analyses. BPA in saliva and urine was determined with liquid chromatography/mass spectrometry. Linear mixed effects regression models were used for statistical analyses. There was a statistically significant increase of salivary BPA concentration directly after placement of the dental polymer-based restorations. Following placement, the concentration of BPA decreased exponentially with time. One week after treatment the BPA level in saliva was only marginally higher than before treatment. In urine, no statistically significant change of the BPA concentration was detected after treatment.
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Registered trials
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