Evidence map›Paper›PMID 31392562›Full record

SynthesisCerebellum (London, England)2019

Exercise and Physical Therapy Interventions for Children with Ataxia: A Systematic Review.

Helen Hartley, Elizabeth Cassidy, Lisa Bunn, Ram Kumar, Barry Pizer, Steven Lane, Bernie Carter

3 registry-linked trialsOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Cerebellum (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05340049 nacompletednot on this mapstarted 2021, after this paper: background citation

Early Craniosacral Therapy Improves Infant Neurodevelopment in Apparently Healthy Children.

TypeinterventionalSponsorClinica Gema LeonRan2021 to 2022Enrolled120ConditionsChild Development DisorderArmsAcademic behavioral intervention of teachers, Therapy sessions
NCT06692296 narecruitingnot on this mapstarted 2025, after this paper: background citation

Studio Pilota Sull'Efficacia Della Pedana Stabilometrica Nel Trattamento Del Paziente Con Atassia di Friedreich

TypeinterventionalSponsorIRCCS Eugenio MedeaRan2025 to 2027Enrolled24ConditionsFriedreich AtaxiaArmsBalance training over stabilometric platform, Balance training by means of conventional rehabilitation
NCT07265154 narecruitingnot on this mapstarted 2026, after this paper: background citation

Gait Training and Balance in Above Knee Amputation Patients Using Artificial Intelligence

TypeinterventionalSponsorSouth Valley UniversityRan2026 to 2026Enrolled40ConditionsAbove Knee Amputation, AmputationArmsArtificial Intelligence
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Heliyon · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Pallidal degenerations and related disorders: an update.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  12. Article
  13. Rehabilitation in patients with cerebellar ataxias.Arquivos de neuro-psiquiatria · 2022
    Article
  14. Article
  15. Article
  16. Update on the Treatment of Ataxia: Medication and Emerging Therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Helen HartleyPhysiotherapy Department, Alder Hey Children's NHS Foundation Trust, Eaton Road, Liverpool, L12 2AP, UK. Helen.hartley@alderhey.nhs.uk.
Elizabeth CassidyPhysiotherapy Department, Lunex International University of Health, Exercise and Sports, Differdange, Luxembourg.
Lisa BunnSchool of Health Professions, University of Plymouth, Plymouth, UK.
Ram KumarNeurology Department, Alder Hey Children's NHS Foundation Trust, Eaton Road, Liverpool, L12 2AP, UK.
Barry PizerOncology Department, Alder Hey Children's NHS Foundation Trust, Eaton Road, Liverpool, L12 2AP, UK.
Steven LaneUniversity of Liverpool, Liverpool, UK.
Bernie CarterEdge Hill University, Ormskirk, UK. bernie.carter@edgehill.ac.uk.
Alder Hey Children's NHS Foundation Trust · GBEdge Hill University · GBUniversity of Liverpool · GBUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effectiveness of exercise and physical therapy for children with ataxia is poorly understood. The aim of this systematic review was to critically evaluate the range, scope and methodological quality of studies investigating the effectiveness of exercise and physical therapy interventions for children with ataxia. The following databases were searched: AMED, CENTRAL, CDSR, CINAHL, ClinicalTrials.gov, EMBASE, Ovid MEDLINE, PEDro and Web of Science. No limits were placed on language, type of study or year of publication. Two reviewers independently determined whether the studies met the inclusion criteria, extracted all relevant outcomes, and conducted methodological quality assessments. A total of 1988 studies were identified, and 124 full texts were screened. Twenty studies were included in the review. A total of 40 children (aged 5-18 years) with ataxia as a primary impairment participated in the included studies. Data were able to be extracted from eleven studies with a total of 21 children (aged 5-18 years), with a range of cerebellar pathology. The studies reported promising results but were of low methodological quality (no RCTs), used small sample sizes and were heterogeneous in terms of interventions, participants and outcomes. No firm conclusions can be made about the effectiveness of exercise and physical therapy for children with ataxia. There is a need for further high-quality child-centred research.

Indexed as

Physical Therapy ModalitiesAtaxiaChildExercise TherapyHumansProspective StudiesRetrospective StudiesAtaxiaExercisePaediatricsPhysical therapySystematic review

Identifiers

PMID31392562
PMCPMC6761087
OpenAlexW2966861638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.