Evidence map›Paper›PMID 31392477›Full record

Observational studyEuropean radiology2020

Mitral annular plane systolic excursion by cardiac MR is an easy tool for optimized prognosis assessment in ST-elevation myocardial infarction.

Agnes Mayr, Mathias Pamminger, Martin Reindl, Simon Greulich, Sebastian J Reinstadler, Christina Tiller, Magdalena Holzknecht, Timo Nalbach, David Plappert, Christof Kranewitter and 2 more

Abstract readObservational Study
In one paragraph

Observational study in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Agnes Mayr *University Clinic of Radiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria. agnes.mayr@tirol-kliniken.at.
Mathias Pamminger *University Clinic of Radiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Martin ReindlUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Simon GreulichDepartment of Cardiology and Cardiovascular Diseases, University Hospital Tübingen, Otfried Müller-Straße 10, 72076, Tübingen, Germany.
Sebastian J ReinstadlerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Christina TillerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Magdalena HolzknechtUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Timo NalbachUniversity Clinic of Radiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
David PlappertUniversity Clinic of Radiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Christof KranewitterUniversity Clinic of Radiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Gert KlugUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Bernhard MetzlerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was to assess the comparative prognostic value of mitral annular plane systolic excursion (MAPSE) versus left ventricular ejection fraction (LVEF), measured by cardiac magnetic resonance (CMR) imaging in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI).

methodsCMR was performed in 255 STEMI patients within 2 days (interquartile range (IQR) 2-4 days) after infarction. CMR included MAPSE measurement on CINE 4-chamber view. Patients were followed for major adverse cardiovascular events (MACE)-death, non-fatal myocardial re-infarction, stroke, and new congestive heart failure.

resultsPatients with MACE (n = 35, 14%, median follow-up 3 years [IQR 1-4 years]) showed significantly lower MAPSE (8 mm [7-8.8] vs. 9.6 mm [8.1-11.5], p < 0.001). The association between decreased MAPSE (< 9 mm, optimal cut-off value by c-statistics) remained significant after adjustment for independent clinical and CMR predictors of MACE. The AUC of MAPSE for the prediction of MACE was 0.74 (CI 95% 0.65-0.82), significantly higher than that of LVEF (0.61 [CI 95% 0.50-0.71]; p < 0.001).

conclusionsReduced long-axis function assessed with MAPSE measurement using CINE CMR independently predicts long-term prognosis following STEMI. Moreover, MAPSE provided significantly higher prognostic implication in comparison with conventional LVEF measurement. KEY POINTS: • MAPSE determined by CMR independently predicts long-term prognosis following STEMI. • MACE-free survival is significantly higher in patients with MAPSE ≥ 9 mm than < 9 mm. • MAPSE provides significantly higher prognostic implication than conventional LVEF.

Indexed as

FemaleHeart VentriclesHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisProspective StudiesST Elevation Myocardial InfarctionStroke VolumeVentricular Dysfunction, LeftMagnetic resonance imagingPrognosisST-elevation myocardial infarction

Identifiers

PMID31392477
PMCPMC6890588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.