Evidence map›Paper›PMID 31392406›Full record

ArticleMolecular genetics and genomics : MGG2020

XG-PseU: an eXtreme Gradient Boosting based method for identifying pseudouridine sites.

Kewei Liu, Wei Chen, Hao Lin

Erratum issuedAbstract read
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In one paragraph

Article in Molecular genetics and genomics : MGG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. LBCE-XGB: A XGBoost Model for Predicting Linear B-Cell Epitopes Based on BERT Embeddings.Interdisciplinary sciences, computational life sciences · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kewei LiuSchool of Life Sciences, and Center for Genomics and Computational Biology, North China University of Science and Technology, Tangshan, 063000, China.
Wei ChenSchool of Life Sciences, and Center for Genomics and Computational Biology, North China University of Science and Technology, Tangshan, 063000, China. chenweiimu@gmail.com.
Hao LinKey Laboratory for Neuro-Information of Ministry of Education, School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, 610054, China. hlin@uestc.edu.cn.

Funding

National Natural Science Foundation of China 31771471National Natural Science Foundation of China 61772119
6 · The paper itself

Abstract

As one of the most popular post-transcriptional modifications, pseudouridine (Ψ) participates in a series of biological processes. Therefore, the efficient detection of pseudouridine sites is very important in revealing its functions in biological processes. Although experimental techniques have been proposed for identifying Ψ sites at single-base resolution, they are still labor intensive and expensive. Recently, to fill the experimental method's gap, computational methods have been proposed for identifying Ψ sites. However, their performances are still unsatisfactory. In this paper, we proposed an eXtreme Gradient Boosting (xgboost)-based method, called XG-PseU, to identify Ψ sites based on the optimal features obtained using the forward feature selection together with increment feature selection method. Our results demonstrated that XG-PseU is superior or at least complementary to existing methods for identifying pseudouridine sites. Finally, a freely available online web server for XG-PseU was established at http://www.bioml.cn/. We wish that XG-PseU will become a useful tool for computationally identifying Ψ sites.

Indexed as

AnimalsComputational BiologyHumansMicePseudouridineRNA Processing, Post-TranscriptionalSaccharomyces cerevisiaePseudouridineeXtreme Gradient BoostingFeature selectionPseudouridineWeb server

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.