Evidence map›Paper›PMID 31392382›Full record

ArticleEuropean biophysics journal : EBJ2019

Impact of semen-derived amyloid (SEVI) on sperm viability and motility: its implication in male reproductive fitness.

Vijay Kumar, Pradeep G Kumar, Jay Kant Yadav

Abstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Amyloid-mediated RNA uptake by sperm for embryonic delivery.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Vijay KumarDepartment of Biotechnology, Central University of Rajasthan, NH-8 Jaipur-Ajmer Highway, Bandarsindri, Kishangarh, Ajmer, Rajasthan, 305817, India.
Pradeep G KumarMolecular Reproduction Division, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, Kerala, 695014, India.
Jay Kant YadavDepartment of Biotechnology, Central University of Rajasthan, NH-8 Jaipur-Ajmer Highway, Bandarsindri, Kishangarh, Ajmer, Rajasthan, 305817, India. jaykantyadav@curaj.ac.in.ORCID http://orcid.org/0000-0003-1985-5925
Central University of Rajasthan · INRajiv Gandhi Centre for Biotechnology · IN

Funding

Science and Engineering Research Board SB/YS/LS-130/2013
6 · The paper itself

Abstract

Human semen contains a large number of macromolecules, including proteins/enzymes and carbohydrates, regulating and protecting sperm cells. Proteomic analysis of human seminal fluid led to the discovery of semen amyloids derived from short peptide fragments of the proteins prostatic acid phosphatase (PAP) and semenogelin (SG) which are known to play a crucial role in enhancing HIV infection. However, the relevance of their existence in human semen and role in maintaining sperm behavior remains unclear. Distinct physiological, biochemical, and biophysical attributes might cause these amyloids to influence sperm behavior positively or negatively, affecting fertilization or other reproductive processes. We assessed the direct effect of amyloids derived from a PAP

Indexed as

Amino Acid SequenceAmyloidHumansMaleProtein AggregatesReproductionSemenSpermatozoaSperm MotilityTissue SurvivalAmyloidProtein AggregatesMale sterilityPAP248–286Semen-derived amyloidsSEVI

Identifiers

PMID31392382
OpenAlexW2965811541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.