Evidence map›Paper›PMID 31392301›Full record

ArticleAnimal models and experimental medicine2019

Effect of different anesthetic mixtures-ketamine-xylazine, ketamine-acepromazine and tiletamine-zolazepam-on the physiological and blood biochemistry parameters of male rhesus monkeys (

Braulio Hernández-Godínez, Herlinda Bonilla Jaime, Adrián Poblano, Marcela Arteaga-Silva, Ameyalli Medina Hernández, Armando Contreras-Uribe, Alejandra Ibáñez-Contreras

Open access · diamondAbstract read
In one paragraph

Article in Animal models and experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Braulio Hernández-GodínezPosgrado en Ciencias Biológicas y de la Salud Unidad Iztapalapa Universidad Autónoma Metropolitana Ciudad de México México.
Herlinda Bonilla JaimeDepartamento Biología de la Reproducción Unidad Iztapalapa Universidad Autónoma Metropolitana Ciudad de México México.
Adrián PoblanoLaboratorio de Neurofisiología Cognoscitiva Instituto Nacional de Rehabilitación Ciudad de México México.
Marcela Arteaga-SilvaDepartamento Biología de la Reproducción Unidad Iztapalapa Universidad Autónoma Metropolitana Ciudad de México México.
Ameyalli Medina HernándezInvestigación Biomédica Aplicada (INBIOMA) S.A.S. de C.V. Ciudad de México México.
Armando Contreras-UribeInvestigación Biomédica Aplicada (INBIOMA) S.A.S. de C.V. Ciudad de México México.
Alejandra Ibáñez-ContrerasInvestigación Biomédica Aplicada (INBIOMA) S.A.S. de C.V. Ciudad de México México.ORCID 0000-0001-6852-0852
Instituto Nacional de Rehabilitación · MXUniversidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnesthetic agents are commonly utilized in the handling of non-human primates for prevent the stress caused in physical exploration or physical restrain. For this reason, the objective of this work was to describe the effect of age and dissociative anesthetics (ketamine and tiletamine), and their combinations with acepromazine, xylazine and zolazepam, on the physiological and blood biochemical parameters in

methodsEighty male

resultsStatistical analyses revealed significant differences in the physiological parameters between the ketamine-acepromazine and ketamine-xylazine groups compared to the control group. The analysis of blood biochemistry found significant differences by age and by anesthetic mixture among all groups.

conclusionThese findings contribute to standardizing this animal model in biological research.

Indexed as

acepromazineanesthesiablood biochemistryketamineMacaca mulattaphysiologic parameterstiletaminexylazinezolazepam

Identifiers

PMID31392301
PMCPMC6600652
OpenAlexW2922614688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.