Evidence map›Paper›PMID 31392081›Full record

ArticleAmerican journal of cancer research2019

Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection.

Hye Jin Lee, Emily B Ehlerding, Dawei Jiang, Todd E Barnhart, Tianye Cao, Weijun Wei, Carolina A Ferreira, Peng Huang, Jonathan W Engle, Weibo Cai

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Intraoperative fluorescence molecular imaging accelerates the coming of precision surgery in China.European journal of nuclear medicine and molecular imaging · 2022
    Review
  6. Advances in aptamer-based nuclear imaging.European journal of nuclear medicine and molecular imaging · 2022
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Tissue Factor-Targeted ImmunoPET Imaging and Radioimmunotherapy of Anaplastic Thyroid Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Hye Jin LeeDepartment of Pharmaceutical Sciences, University of Wisconsin-Madison Madison, WI 53705, USA.
Emily B EhlerdingDepartment of Medical Physics, University of Wisconsin-Madison Madison, WI 53705, USA.
Dawei JiangDepartment of Radiology, University of Wisconsin-Madison Madison, WI 53705, USA.
Todd E BarnhartDepartment of Medical Physics, University of Wisconsin-Madison Madison, WI 53705, USA.
Tianye CaoDepartment of Radiology, University of Wisconsin-Madison Madison, WI 53705, USA.
Weijun WeiDepartment of Radiology, University of Wisconsin-Madison Madison, WI 53705, USA.
Carolina A FerreiraDepartment of Biomedical Engineering, University of Wisconsin-Madison Madison, WI 53706, USA.
Peng HuangGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Carson International Cancer Center, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center, Shenzhen University Shenzhen 518060, China.
Jonathan W EngleDepartment of Medical Physics, University of Wisconsin-Madison Madison, WI 53705, USA.
Weibo CaiDepartment of Pharmaceutical Sciences, University of Wisconsin-Madison Madison, WI 53705, USA.
University of Wisconsin–Madison · USShenzhen University · CN

Funding

WATER DISTRIB:PHYSICAL PROPERT:PIZZA &LMPS MOZZARELLA CHEESES:EARLY STAGE MATURP41RR002301 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 1985 to 2011
$13.0M
Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
NCRR NIH HHS P41 RR002301NIGMS NIH HHS T32 GM008505
6 · The paper itself

Abstract

Pertuzumab is clinically employed in the treatment of cancers over-expressing human epidermal growth factor receptor 2 (HER2). Herein, we developed dual-labeled pertuzumab with a radionuclide (

Indexed as

89ZrHuman epidermal growth factor receptor 2 (HER2)image-guided surgerynear-infrared fluorescence (NIRF) imagingovarian cancerpertuzumabpositron emission tomography (PET)

Identifiers

PMID31392081
PMCPMC6682714
OpenAlexW2984033415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.