Evidence map›Paper›PMID 31391892›Full record

ArticleMedChemComm2019

The synthesis and biological evaluation of novel gardenamide A derivatives as multifunctional neuroprotective agents.

Zuzhi Zhang, Yujun Wang, Yanchun Zhang, Jiaming Li, Weijun Huang, Lei Wang

Open access · bronzeAbstract read
In one paragraph

Article in MedChemComm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Terpenoid natural products exert neuroprotectionFrontiers in pharmacology · 2022
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zuzhi ZhangDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.
Yujun WangDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.
Yanchun ZhangDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.ORCID 0000-0002-9694-9768
Jiaming LiDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.
Weijun HuangDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.
Lei WangDepartment of Medicinal Chemistry , Anhui University of Chinese Medicine , 103 Meishan Road , Hefei 230031 , PR China . Email: yczhang2017@163.com.
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel series of gardenamide A derivatives was synthesized as potential anti-Alzheimer's disease agents. The neuroprotective effects of these multifunctional agents against oxygen-glucose deprivation (OGD)-induced neurotoxicity in rat cortical neurons, and hydrogen peroxide (H

Identifiers

PMID31391892
PMCPMC6640559
OpenAlexW2946627218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.