ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2019
The Mean Platelet Volume in the Prognosis of Coronary Artery Disease Severity and Risk Stratification of Acute Coronary Syndromes.
Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Mean platelet volume as a translational biomarker for cardiovascular risk stratification with perspectives for medical education: a systematic review.Global cardiology science & practice · 2026Review
- Hematological parameters as predictors of complex angiographic coronary lesions in patients with acute myocardial infarction.PloS one · 2026Article
- Article
- Machine Learning Efficiency in Predicting Obstructive Coronary Artery Disease in Patients with Non-ST Elevation Acute Coronary Syndrome in the First Hours of Admission.Sovremennye tekhnologii v meditsine · 2025Article
- The relationship between hematological parameters and coronary angiographic lesions.Frontiers in cardiovascular medicine · 2025Review
- The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients' 30-day mortality after liver transplantation.Clinical and experimental hepatology · 2022Article
- Interaction of Lipids, Mean Platelet Volume, and the Severity of Coronary Artery Disease Among Chinese Adults: A Mediation Analysis.Frontiers in cardiovascular medicine · 2022Article
- The Association of 25-Hydroxy Vitamin D level with Mean Platelet Volume in Patients with Acute Coronary Syndrome.Cardiovascular & hematological disorders drug targets · 2022Article
- New Markers of Platelet Activation and Reactivity and Oxidative Stress Parameters in Patients Undergoing Coronary Artery Bypass Grafting.Oxidative medicine and cellular longevity · 2021Article
- Selected Hematological Biomarkers to Predict Acute Mortality in Emergency Department Patients. Recent Polish Hospital Statistics.Disease markers · 2020Article
- Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coronary Intervention.Cardiovascular therapeutics · 2020Observational
- Platelet distribution width-a prognosis marker in patients with chronic heart failure.Porto biomedical journalArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPlatelets play a crucial role in thrombotic episodes. Mean Platelet Volume (MPV) is the primary indicator of platelet's activation; its measurement is easy and time-effective.
aimWe tested the hypothesis that MPV is correlated with SYNTAX score in patients that suffered from an Acute Coronary Syndrome (ACS). MATERIAL AND
methodsOne hundred and four (104) patients (79 male-25 female, mean age 64.2±11.1 years), who were hospitalized for an ACS and underwent coronary angiography, were included in the study. Syntax score, as an indicator of the severity of coronary artery disease (CAD), was calculated. We tried to investigate the correlation between the first measured MPV, CRP, Creatinine and high sensitivity Troponin with the Syntax score of the patient and the association of MPV and a possible Major Advanced Cardiac Event (MACE) during hospitalization.
resultsThe patients were divided into four groups according to the SYNTAX score: Group A (SYNTAX score: 0, n=12), group B: Mild CAD (SYNTAX score: 1-22, n=68), group C: Moderate CAD (SYNTAX score: 23-32, n=12), and group D: Severe CAD (SYNTAX score: ≥ 33, n=12). Four patients (3.8%) developed a MACE during their hospitalization. MPV was significantly correlated to Syntax score (r=0.658, p<0.001) and was found to be an independent predictor factor of MACE with HR=6.8 (95% Confidence Interval 1.46-33.36). The cut-off value of MPV was 7.5 with a sensitivity of 98% and a specificity of 30.8%.
conclusionWe determined a positive correlation between MPV and Syntax score, transforming this simple test in a possible factor of risk stratification in ACS.
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