ArticleIndian journal of anaesthesia2019
Is COMBIPECS the answer to perioperative analgesia for breast surgery? A double blinded randomized controlled trial.
Article in Indian journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Efficacy of regional anesthesia techniques for postoperative analgesia in patients undergoing major oncologic breast surgeries: a systematic review and network meta-analysis of randomized controlled trials.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Pooled it
- Evaluation of postoperative pain in patients undergoing modified radical mastectomy with pectoralis or serratus-intercostal fascial plane blocks.Korean journal of anesthesiology · 2020Trial
- Postoperative Nausea and Vomiting in Female Patients Undergoing Breast and Gynecological Surgery: A Narrative Review of Risk Factors and Prophylaxis.Frontiers in medicine · 2022Review
- Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study.Frontiers in medicine · 2022Article
- Direct PEC block: Simplified and effective alternative when US-PEC block is difficult.Indian journal of anaesthesia · 2020Article
- Erector spinae plane block for breast oncological procedure as a surrogate to general anaesthesia: A retrospective study.Indian journal of anaesthesia · 2020Article
- Pectoral Nerve (PECs) block for postoperative analgesia-a systematic review and meta-analysis with trial sequential analysis.International journal of physiology, pathophysiology and pharmacology · 2020Article
- Pectoral nerve versus erector spinae block for breast surgeries: A randomised controlled trial.Indian journal of anaesthesia · 2019Article
- Regional block: Walking away from central to peripheral nerves and planes for local anaesthetic drug deposition.Indian journal of anaesthesia · 2019Article
- Comparison of ropivacaine alone versus dexmedetomidine or ketamine as an adjuvant for pectoral type II nerve blocks in patients undergoing mastectomy - A randomized controlled trial.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsPecs block and its variations provides perioperative analgesia, reduce PONV and other opioid related side effects. We hypothesized that COMIBPES block in addition to general anaesthesia will provide better postoperative analgesia when compared to general anaesthesia alone in breast cancer surgery patients.
methodsAfter obtaining permission from the institutional review board and registering the trial with Clinical Trials Registry of India (CTRI), we conducted a double blinded randomized controlled trial of 100 patients posted for elective breast surgery with axillary dissection. Patients were divided into two groups, P (Pecs block) and C (control). Intraoperative analgesia, postoperative analgesia, postoperative nausea vomiting (PONV) and shoulder mobility on first postoperative day (POD1) were noted. Primary outcomes were the pain scores measured by visual analog scale (VAS) and cumulative intravenous morphine consumption from patient controlled analgesia (PCA) pump at measurement intervals of 0, 1, 4, 8, 12 and 24 hours postoperatively.
resultsIntraoperatively, Group P patients did not require any additional analgesia, whereas all the patients in Group C required additional intraoperative morphine (mean, SD: 5.12, 2.63 mg, compared to nil in group P,
conclusionCOMBIPECS block is a valuable addition to general anaesthesia for breast cancer surgery as it reduces pain and PONV while allowing better postoperative shoulder mobility.
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