ArticleNature2019
Opposing T cell responses in experimental autoimmune encephalomyelitis.
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Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.
0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
130 citing papers in PubMed, 200 citations in OpenAlex.
- Regulatory T cell induction strategies and applications in the treatment of immune and non-immune diseases.Signal transduction and targeted therapy · 2026Review
- Immune Cell Causality and Glucocorticoid Trade-Off in Frozen Shoulder: Integrative MR-RNA-Seq Analysis.Biomedicines · 2026Article
- CD8+ Regulatory T Cells.Annual review of immunology · 2026Review
- Deletion of Lymphatic PD-L1 Protects Mice From Severe Autoimmune Encephalitis.European journal of immunology · 2026Article
- Donor-derived CD8bioRxiv : the preprint server for biology · 2026Article
- Shared diagnostic biomarkers and diagnostic models of age-related macular degeneration and systemic lupus erythematosus.International ophthalmology · 2026Article
- CD318 expression defines a novel subset of human CD8Science advances · 2026Article
- Stem cell-derived extracellular vesicles as immunomodulatory agents: targeting pathological crosstalk in systemic lupus erythematosus and multiple sclerosis.Frontiers in medicine · 2026Review
- Selective inhibition of mitochondrial Kv1.3 prevents and alleviates multiple sclerosis in vivo.EMBO molecular medicine · 2025Article
- Cytotoxic T Cells: Kill, Memorize, and Mask to Maintain Immune Homeostasis.International journal of molecular sciences · 2025Review
- Notch2-expressing CD4Cellular & molecular immunology · 2025Article
- Regulatory KIRScience translational medicine · 2025Article
- TGFα controls checkpoints in CNS resident and infiltrating immune cells to promote resolution of inflammation.Nature communications · 2025Article
- Multiple Sclerosis: A Story of the Interaction Between Gut Microbiome and Components of the Immune System.Molecular neurobiology · 2025Review
- Selection of therapeutically effective T-cell receptors from the diverse tumor-bearing repertoire.Journal for immunotherapy of cancer · 2025Article
- Molecular probes for in vivo optical imaging of immune cells.Nature biomedical engineering · 2025Review
- High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits.Nature biotechnology · 2025Article
- Age-Dependent Bi-Phasic Dynamics of Ly49Aging cell · 2025Article
- Phenotypic and functional dysregulations of CD8 + T Cells in myasthenia gravis.Clinical and experimental medicine · 2025Article
- Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets.Neuron · 2025Review
70 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Naresha SaligramaDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Fan Zhao *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Michael J Sikora *Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
William S SerratelliInstitute of Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.
Ricardo A FernandesDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
David M LouisInstitute of Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.
Winnie YaoInstitute of Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.
Xuhuai JiHuman Immune Monitoring Center, Stanford University School of Medicine, Stanford, CA, USA.
Juliana IdoyagaDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Vinit B MahajanByers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA, USA.
Lars M SteinmetzDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Yueh-Hsiu ChienDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Stephen L HauserDepartment of Neurology and UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Jorge R OksenbergDepartment of Neurology and UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
K Christopher GarciaDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Mark M DavisDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. mmdavis@stanford.edu.
Stanford University · USUniversity of California, San Francisco · USEuropean Molecular Biology Laboratory · DEPalo Alto Veterans Institute for Research · US
Funding
Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5MINSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2MTCR recognition of MHC class II peptide compexes in multiple sclerosisP01AI045757 · NIAID · DANA-FARBER CANCER INSTITUTE · PI KUCHROO, VIJAY K., LOVE, JOHN CHRISTOPHER · 1999 to 2017
$22.8MThe Role of B cells in the Origin and Progression of Multiple SclerosisR35NS111644 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEPHEN L HAUSER · 2019 to 2026
$9.1MGENE LINKAGE STUDY OF MULTIPLE SCLEROSIS SIBLING PAIRSR01NS026799 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAUSER, STEPHEN L, OKSENBERG, JORGE R. · 1989 to 2018
$6.8MStructural correlates of T cell receptor signalingR01AI103867 · NIAID · STANFORD UNIVERSITY · PI Kenan Christopher GARCIA · 2014 to 2026
$5.3MHarnessing human dendritic cell subsets for the design of novel immunotherapiesDP2AR069953 · NIAMS · STANFORD UNIVERSITY · PI IDOYAGA, JULIANA · 2015 to 2015
$2.4MMechanism-based therapies for photoreceptor degenerationR01EY025225 · NEI · UNIVERSITY OF IOWA · PI MAHAJAN, VINIT B · 2015 to 2018
$1.3MHigh Throughput DNA Sequencer UpgradeS10OD018220 · OD · STANFORD UNIVERSITY · PI COLLER, JOHN · 2014 to 2014
$596kHoward Hughes Medical InstituteNEI NIH HHS R01 EY025225NHGRI NIH HHS T32 HG000044NIAID NIH HHS P01 AI045757NIAID NIH HHS R01 AI103867NIAID NIH HHS U19 AI057229NIAMS NIH HHS DP2 AR069953NIH HHS S10 OD018220NINDS NIH HHS R01 NS026799NINDS NIH HHS R35 NS111644Wellcome Trust WT101609MA
Abstract
Experimental autoimmune encephalomyelitis is a model for multiple sclerosis. Here we show that induction generates successive waves of clonally expanded CD4
Indexed as
AdultAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCeliac DiseaseClone CellsEncephalomyelitis, Autoimmune, ExperimentalFemaleH-2 AntigensHumansImmunizationLymphocyte ActivationMaleMiceMice, Inbred C57BLMiddle AgedH-2 AntigensMyelin-Associated GlycoproteinReceptors, Antigen, T-Cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.