ArticleScientific reports2019
Glycerylphytate compounds with tunable ion affinity and osteogenic properties.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Inositol Hexaphosphate in Bone Health and Disease.Biomolecules · 2024Review
- Adsorption of cationic/anionic dyes and endocrine disruptors by yeast/cyclodextrin polymer composites.RSC advances · 2024Article
- Characterization of a putative metal-dependent PTP-like phosphatase from Lactobacillus helveticus 2126.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Tetracalcium Phosphate Biocement Hardened with a Mixture of Phytic Acid-Phytase in the Healing Process of Osteochondral Defects in Sheep.International journal of molecular sciences · 2023Article
- Interfacial Electrostatic Self-Assembly of Amyloid Fibrils into Multifunctional Protein Films.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- New Insights into thePharmaceutics · 2023Article
- Emerging Biofabrication Techniques: A Review on Natural Polymers for Biomedical Applications.Polymers · 2021Review
- Microfluidics generation of chitosan microgels containing glycerylphytate crosslinker for in situ human mesenchymal stem cells encapsulation.Materials science & engineering. C, Materials for biological applications · 2021Article
- Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytic acid (PA) is a natural-occurring antioxidant, which plays an important role in many biological processes. PA is recognized as a potent inhibitor of lipid peroxidation because of its high affinity to multivalent cations, and it can play a role in osteogenic processes. However, its powerful chelating capacity is controversial because it can lead to a severe reduction of mineral availability in the organism. For this reason, compounds with beneficial biological properties of PA, but a modular ion binding capacity, are of high interest. In this work, we report the synthesis and physicochemical characterization of two hydroxylic derivatives of PA, named glycerylphytates (GPhy), through a condensation reaction of PA with glycerol (G). Both derivatives present antioxidant properties, measured by ferrozine/FeCl
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.