Evidence map›Paper›PMID 31391240›Full record

ArticleJournal of cell science2019

Altering integrin engagement regulates membrane localization of K

Swarnali Sengupta, Katheryn E Rothenberg, Hanjun Li, Brenton D Hoffman, Nenad Bursac

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Extracellular matrix stiffness regulates degradation of MST2 via SCFBiochimica et biophysica acta. General subjects · 2022
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Swarnali SenguptaDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0001-5532-7818
Katheryn E RothenbergDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-8191-7528
Hanjun LiDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Brenton D HoffmanDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA nbursac@duke.edu brenton.hoffman@duke.edu.ORCID 0000-0003-2296-1331
Nenad BursacDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA nbursac@duke.edu brenton.hoffman@duke.edu.ORCID 0000-0002-5688-6061
Duke University · US

Funding

Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7M
In Vitro and In Situ Engineering of Fibroblasts for Cardiac RepairR01HL132389 · NHLBI · DUKE UNIVERSITY · PI BURSAC, NENAD · 2016 to 2019
$2.0M
Engineering of Human Excitable Tissues from Unexcitable CellsR01HL126524 · NHLBI · DUKE UNIVERSITY · PI BURSAC, NENAD · 2016 to 2019
$1.9M
NHLBI NIH HHS R01 HL126524NHLBI NIH HHS R01 HL132389NHLBI NIH HHS U01 HL134764
6 · The paper itself

Abstract

How ion channels localize and distribute on the cell membrane remains incompletely understood. We show that interventions that vary cell adhesion proteins and cell size also affect the membrane current density of inward-rectifier K

Indexed as

AnimalsEndocytosisFemaleHEK293 CellsHumansIntegrinsIon Channel GatingMembrane PotentialsPotassium Channels, Inwardly RectifyingRatsRats, Sprague-DawleyIntegrinsKCNJ2 protein, humanKCNJ2 protein, ratPotassium Channels, Inwardly RectifyingCardiac potassium channelEndocytosisFocal adhesionMechanotransductionMicropatterning

Identifiers

PMID31391240
PMCPMC6771140
OpenAlexW2965856570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.