Evidence map›Paper›PMID 31391218›Full record

ArticleRNA (New York, N.Y.)2019

TCF3 mutually exclusive alternative splicing is controlled by long-range cooperative actions between hnRNPH1 and PTBP1.

Takashi Yamazaki, Lizhi Liu, James L Manley

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. HNRNPH1-mediated splicing events regulatebioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Crucial roles of different RNA-binding hnRNP proteins in Stem Cells.International journal of biological sciences · 2021
    Review
  10. Burkitt lymphoma-relatedRNA biology · 2020
    Article
  11. Article
  12. Article
  13. The HNRNPF/H RNA binding proteins and disease.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Takashi YamazakiDepartment of Biological Sciences, Columbia University, New York, New York 10027, USA.
Lizhi LiuDepartment of Biological Sciences, Columbia University, New York, New York 10027, USA.
James L ManleyDepartment of Biological Sciences, Columbia University, New York, New York 10027, USA.
Columbia University · US

Funding

Regulation of RNA processing: Mechanisms and ConsequencesR35GM118136 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI James L. Manley · 2016 to 2026
$8.9M
NIGMS NIH HHS R35 GM118136
6 · The paper itself

Abstract

TCF3, also known as E2A, is a well-studied transcription factor that plays an important role in stem cell maintenance and hematopoietic development. The

Indexed as

Alternative SplicingBasic Helix-Loop-Helix ProteinsDEAD-box RNA HelicasesExonsHeLa CellsHeterogeneous-Nuclear RibonucleoproteinsHumansIntronsPolypyrimidine Tract-Binding ProteinProtein BindingBasic Helix-Loop-Helix ProteinsDDX21 protein, humanDEAD-box RNA HelicasesHeterogeneous-Nuclear RibonucleoproteinsPolypyrimidine Tract-Binding ProteinPTBP1 protein, humanTCF3 protein, humanalternative splicinghnRNPHintronic splicing silencerPTBP1TCF3

Identifiers

PMID31391218
PMCPMC6795145
OpenAlexW2964486752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.