Evidence map›Paper›PMID 31391195›Full record

ArticleDevelopment (Cambridge, England)2019

The Egalitarian binding partners Dynein light chain and Bicaudal-D act sequentially to link mRNA to the Dynein motor.

Chandler H Goldman, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B Gonsalvez

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

  1. AnbioRxiv : the preprint server for biology · 2026
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  6. Review
  7. Article
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  9. The dynamic duo of microtubule polymerase Mini spindles/XMAP215 and cytoplasmic dynein is essential for maintainingProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. bioRxiv : the preprint server for biology · 2023
    Article
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  13. Review
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  15. Article
  16. Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chandler H GoldmanCellular Biology and Anatomy, Medical College of Georgia, Augusta University, 1459 Laney Walker Blvd, Augusta, GA 30912, USA.
Hannah NeiswenderCellular Biology and Anatomy, Medical College of Georgia, Augusta University, 1459 Laney Walker Blvd, Augusta, GA 30912, USA.
Rajalakshmi Veeranan-KarmegamCellular Biology and Anatomy, Medical College of Georgia, Augusta University, 1459 Laney Walker Blvd, Augusta, GA 30912, USA.
Graydon B GonsalvezCellular Biology and Anatomy, Medical College of Georgia, Augusta University, 1459 Laney Walker Blvd, Augusta, GA 30912, USA ggonsalvez@augusta.edu.ORCID 0000-0002-4458-8497
Augusta University · US

Funding

A molecular examination of mRNA localization and cell polarizationR01GM100088 · NIGMS · AUGUSTA UNIVERSITY · PI GONSALVEZ, GRAYDON · 2013 to 2021
$2.7M
NIGMS NIH HHS R01 GM100088
6 · The paper itself

Abstract

A conserved mechanism of polarity establishment is the localization of mRNA to specific cellular regions. Although it is clear that many mRNAs are transported along microtubules, much less is known about the mechanism by which these mRNAs are linked to microtubule motors. The RNA binding protein Egalitarian (Egl) is necessary for localization of several mRNAs in

Indexed as

AnimalsCell LineDrosophila melanogasterDrosophila ProteinsDyneinsMicrotubulesOocytesOogenesisProtein BindingRNA InterferenceRNA, MessengerRNA, Small InterferingBicD protein, DrosophilaDrosophila ProteinsDyneinsegl protein, DrosophilaRNA, MessengerRNA, Small InterferingCargo adaptorCell polarityDrosophilaKinesinMolecular motorRNA localization

Identifiers

PMID31391195
PMCPMC6703708
OpenAlexW2965923968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.