Evidence map›Paper›PMID 31391143›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2019

Effects of Pelleting, Irradiation, and Autoclaving of Rodent Feed on MPV and MNV Infectivity.

Sean C Adams, Matthew H Myles, Laura N Tracey, Robert S Livingston, Carrie L Schultz, Jon D Reuter, Mathias Leblanc

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Guidance on Establishing Health Monitoring Panels for Laboratory Mice to Reflect Contemporary Pathogen Prevalence.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Review
  3. Isolation, Characterization, and Epizootiology of Clostridioides cuniculi from Immunodeficient Mice with Enteric Disease.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  4. Effect of Common Variables on Autoclave Best Practices in Rodent Barrier Programs.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  5. Confirmation of Pathogen 'Burnout' in Mouse Colonies with Previous Evidence of Infection with Parvovirus and Rotavirus.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  6. Article
  7. Assessing Elimination of Mouse Kidney Parvovirus from Cages by Mechanical Washing.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sean C AdamsAnimal Resources Department, The Salk Institute for Biological Studies, La Jolla, California.
Matthew H MylesIDEXX BioAnalytics, Columbia, Missouri.
Laura N TraceyPMI Nutrition International, LabDiet, St Louis, Missouri.
Robert S LivingstonIDEXX BioAnalytics, Columbia, Missouri.
Carrie L SchultzPMI Nutrition International, LabDiet, St Louis, Missouri.
Jon D ReuterOffice of Animal Resources, University of Colorado-Boulder, Boulder, Colorado.
Mathias LeblancAnimal Resources Department, The Salk Institute for Biological Studies, La Jolla, California;, Email: mleblanc@salk.edu.
International Plant Nutrition Institute · USSalk Institute for Biological Studies · USUniversity of Colorado Boulder · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Murine norovirus (MNV) and mouse parvovirus (MPV) are among the most common adventitial viruses seen in laboratory mice, and infections arise in barrier facilities despite rigorous biosecurity programs. Some authors have implicated nonsterilized feed as a source of MPV in rodent facilities, but none have conclusively documented viral particles in the feed. In this study, we hypothesized that both viruses can resist the pelleting process but not subsequent irradiation or autoclaving, thus revealing a potential source of outbreaks in rodent facilities. To test this hypothesis, we contaminated powdered feed with 10-fold concentrations of MNV and MPV and fed it to both Swiss Webster (SW) and C57BL/6NTac (B6) mice to determine a 'powdered ID

Indexed as

NorovirusParvovirusAnimal FeedAnimalsCaliciviridae InfectionsFood HandlingMiceMice, Inbred C57BLParvoviridae InfectionsRodent DiseasesRodentia

Identifiers

PMID31391143
PMCPMC6774454
OpenAlexW2968529967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.