ReviewRetrovirology2019
Comparative virology of HTLV-1 and HTLV-2.
Review in Retrovirology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 121 citations in OpenAlex.
- The Prevalence of Syphilis, HTLV I/II, and Malaria Among Blood Donors at the Riyadh Regional Laboratory: A Retrospective Study from Saudi Arabia.Journal of clinical medicine · 2026Article
- Rewiring of the Apoptotic Rheostat in HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma.Cancers · 2026Review
- Prevalence of HTLV-1 and HTLV-2 infection among transgender women in Brazil: A multicenter study.PLoS neglected tropical diseases · 2026Article
- Evaluation of the immunochromatographic assay for HTLV-1/2 detection in Gabon: genotype-specific limitations in Central Africa.Microbiology spectrum · 2026Article
- Review
- Prevalence of human T-cell lymphotropic virus in blood donor screening at the Blood Center: a descriptive study, Mato Grosso, 2018-2021.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Observational
- Article
- Article
- Seroprevalence and molecular detection of human t-cell lymphotropic virus type 1 among multi -transfused patients in Sana'a City, Yemen.BMC infectious diseases · 2025Article
- An unusual case: Adult T-cell leukemia/lymphoma in pediatric patient with human T-lymphotropic virus 1 infection. Clinical implications and therapeutic challenges.JAAD case reports · 2025Article
- Article
- Review
- Human T-Lymphotropic Virus (HTLV): Epidemiology, Genetic, Pathogenesis, and Future Challenges.Viruses · 2025Review
- The role of pioneering transcription factors, chromatin accessibility and epigenetic reprogramming in oncogenic viruses.Frontiers in microbiology · 2025Review
- HTLV-1 and HTLV-2 infections significantly alter small RNA expression in asymptomatic carriers.Frontiers in medicine · 2025Article
- Article
- Review
- Human T-Lymphotropic Virus Type 1 and Cryptococcosis Infection, an Underdiagnosed Association: Case Series and Literature Review.Open forum infectious diseases · 2024Article
- "It's Only a Model": When Protein Structure Predictions Need Experimental Validation, the Case of the HTLV-1 Tax Protein.Pathogens (Basel, Switzerland) · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Shortly after the discovery of HTLV-1, human T-cell leukemia virus type 2 (HTLV-2) was isolated from a patient with hairy cell leukemia. Despite possession of similar structural features to HTLV-1, HTLV-2 has not been definitively associated with lymphoproliferative disease. Since their discovery, studies have been performed with the goal of highlighting the differences between HTLV-1 and HTLV-2. A better understanding of these differences will shed light on the specific pathogenic mechanisms of HTLV-1 and lead to novel therapeutic targets. This review will compare and contrast the two oldest human retroviruses with regards to epidemiology, genomic structure, gene products, and pathobiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.