Evidence map›Paper›PMID 31391057›Full record

ArticleHealth research policy and systems2019

Qualitative Evidence Synthesis (QES) for Guidelines: Paper 1 - Using qualitative evidence synthesis to inform guideline scope and develop qualitative findings statements.

Soo Downe, Kenneth W Finlayson, Theresa A Lawrie, Simon A Lewin, Claire Glenton, Sarah Rosenbaum, María Barreix, Özge Tunçalp

Abstract read
In one paragraph

Article in Health research policy and systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 11 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. The Australian and New Zealand journal of psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soo DowneUniversity of Central Lancashire, Preston, United Kingdom.
Kenneth W FinlaysonUniversity of Central Lancashire, Preston, United Kingdom.
Theresa A LawrieEvidence-based Medicine Consultancy Ltd, Bath, United Kingdom. tess@e-bmc.co.uk.ORCID http://orcid.org/0000-0002-5500-8590
Simon A LewinNorwegian Institute of Public Health, Oslo, Norway.
Claire GlentonNorwegian Institute of Public Health, Oslo, Norway.
Sarah RosenbaumNorwegian Institute of Public Health, Oslo, Norway.
María BarreixDepartment of Reproductive Health and Research including UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.
Özge TunçalpDepartment of Reproductive Health and Research including UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundWHO has recognised the need to ensure that guideline processes are transparent and evidence based, and that the resulting recommendations are relevant and applicable. Along with decision-making criteria that require findings from effectiveness reviews, WHO is increasingly using evidence derived from qualitative evidence syntheses (QES) to inform the values, acceptability, equity and feasibility implications of its recommendations. This is the first in a series of three papers examining the use of QES in developing clinical and health systems guidelines.

methodsWHO convened a group of methodologists involved in developing recent (2010-2018) guidelines that were informed by QES. Using a pragmatic and iterative approach that included feedback from WHO staff and other stakeholders, the group reflected on, discussed and identified key methods and research implications from designing QES and using the resulting findings in guideline development. Our aim in this paper is to (1) describe and discuss how the findings of QES can inform the scope of a guideline and (2) develop findings for key guideline decision-making criteria.

resultsQES resulted in the addition of new outcomes that are directly relevant to service users, a stronger evidence base for decisions about how much effective interventions and related outcomes are valued by stakeholders in a range of contexts, and a more complete database of summary evidence for guideline panels to consider, linked to decisions about values, acceptability, feasibility and equity.

conclusionsRigorously conducted QES can be a powerful means of improving the relevance of guidelines, and of ensuring that the concerns of stakeholders, at all levels of the healthcare system and from a wide range of settings, are taken into account at all stages of the process.

Indexed as

Evidence-Based MedicineHealth Services ResearchPractice Guidelines as TopicQualitative ResearchWorld Health OrganizationCommunicationDecision MakingHealth Knowledge, Attitudes, PracticeHumansMaternal-Child Health ServicesPrenatal CareProfessional RoleSystematic Reviews as TopicVaccinationEvidence-to-decisionGRADEGRADE-CERQualguideline developmentQESqualitative evidence synthesis/synthesesqualitative methodsqualitative reviewWHO guidelines

Identifiers

PMID31391057
PMCPMC6686511

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.