Evidence map›Paper›PMID 31390993›Full record

ArticleBMC nephrology2019

Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study.

Fabian Bock, Thomas G Stewart, Cassianne Robinson-Cohen, Jennifer Morse, Edmond K Kabagambe, Kerri L Cavanaugh, Kelly A Birdwell, Adriana M Hung, Khaled Abdel-Kader, Edward D Siew and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Water intake mediates cross-sectional associations between urinary kidney injury biomarkers and race in emerging adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
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  19. The Vanderbilt O'Brien Kidney Center.American journal of physiology. Renal physiology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Fabian BockDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Thomas G StewartDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Cassianne Robinson-CohenDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jennifer MorseDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Edmond K KabagambeDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN, 37203, USA.
Kerri L CavanaughDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kelly A BirdwellDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Adriana M HungDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Khaled Abdel-KaderDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Edward D SiewDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Elvis A AkwoDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
William J BlotDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN, 37203, USA.
T Alp IkizlerDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Loren LipworthDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN, 37203, USA. loren.lipworth@vumc.org.
Vanderbilt University Medical Center · US

Funding

Southern Community Cohort StudyR01CA092447 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., ZHENG, WEI · 2001 to 2015
$74.0M
Vanderbilt O'Brien Kidney Center - Core D - Clinical and Translational CoreP30DK114809 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DE CAESTECKER, MARK P. · 2017 to 2021
$5.9M
VANDERBILT NEPHROLOGY TRAINING PROGRAMT32DK007569 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRIS, RAYMOND C., IKIZLER, TALAT ALP · 1988 to 2024
$5.8M
American Recovery and Reinvestment Act 3R01CA092447-08S1NCI NIH HHS R01 CA092447NCI NIH HHS R01CA092447NIDDK NIH HHS P30 DK114809NIDDK NIH HHS T32 DK007569
6 · The paper itself

Abstract

introductionThe Southern Community Cohort Study is a prospective study of low socioeconomic status (SES) blacks and whites from the southeastern US, where the burden of end-stage renal disease (ESRD) and its risk factors are high. We tested whether the 2.4-fold elevated risk of ESRD we previously observed in blacks compared to whites was explained by differences in baseline kidney function.

methodsWe conducted a case-cohort study of incident ESRD cases (n = 737) with stored blood and a probability sampled subcohort (n = 4238) and calculated estimated glomerular filtration rate (eGFR) from serum creatinine. 86% of participants were enrolled from community health centers in medically underserved areas and 14% from the general population in 12 states in the southeastern United States. Incident ESRD after entry into the cohort was ascertained by linkage of the cohort with the US Renal Data System (USRDS).

resultsMedian (25th, 75th percentile) eGFR at baseline was 63.3 (36.0, 98.2) ml/min/1.73m

conclusionIn this predominantly lower SES cohort, the racial disparity in ESRD risk is not explained by differences in baseline kidney function.

Indexed as

Black PeopleMedically Underserved AreaWhite PeopleAdultAgedAged, 80 and overBlack or African AmericanCohort StudiesCreatinineFemaleGlomerular Filtration RateHumansIncidenceKidneyKidney Failure, ChronicMaleCreatinineCardiovascular risk factorsCase-cohort studyChronic kidney diseaseDisparityEnd-stage renal diseaseRaceSocioeconomic status

Identifiers

PMID31390993
PMCPMC6686512
OpenAlexW2965545082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.