ArticleAmerican journal of respiratory and critical care medicine2019
Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung.
Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 4 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Review of quantitative and functional lung imaging evidence of vaping-related lung injury.Frontiers in medicine · 2024Pooled it
- Molecular and functional changes in neutrophilic granulocytes induced by nicotine: a systematic review and critical evaluation.Frontiers in immunology · 2023Pooled it
- Chronic health effects associated with electronic cigarette use: A systematic review.Frontiers in public health · 2022Pooled it
- E-cigarette use and respiratory disorders: an integrative review of converging evidence from epidemiological and laboratory studies.The European respiratory journal · 2021Pooled it
- The effect of nicotine delivery system on blood protease levels: a randomized crossover study.Scientific reports · 2025Trial
- Lung lipids associated with smoking and ECIG use in a cross-sectional study and clinical trial.Respiratory research · 2025Trial
- Trial
- Noninvasive repeated sampling technique reveals specific respiratory cytokine signatures for people who use electronic-cigarette and dual-products obtained from a remote cohort of young adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- The triple-hit hypothesis: exploring pulmonary e-cigarette, PMEuropean respiratory review : an official journal of the European Respiratory Society · 2026Review
- Impact of e-cigarette vaping on the immune system across the body.Physiological reviews · 2026Review
- Vaping induces a marked pro-inflammatory state within the lung, which is at least partially due to its immunomodulatory effects.Frontiers in immunology · 2026Article
- Acute respiratory and ocular effects of electronic cigarettes: A pre-post experimental study in healthy users.Tobacco prevention & cessation · 2026Article
- Article
- Risk factors and prediction model for chronic bacterial infection in stable bronchiectasis in Shanghai, China.Frontiers in medicine · 2026Article
- A retrospective analysis of the anatomic characteristics of pulmonary bullae based on chest CT classification and their association with pulmonary function.Frontiers in medicine · 2026Article
- Dynamic changes of immune cells and therapeutic responses in experimental models of COPD.Frontiers in immunology · 2026Review
- Neutrophil store-operated CaJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025Article
- Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025Review
- CYP1B1 Mediates Cigarette Smoke-Induced Lipid Accumulation in Alveolar Type 2 Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- E-Cigarette or Vaping Product Use-Associated Lung Injury: A Comprehensive Review.International journal of environmental research and public health · 2025Review
62 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.