Evidence map›Paper›PMID 31390873›Full record

ArticleAutism : the international journal of research and practice2020

Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior.

Denis G Sukhodolsky, Luc Lecavalier, Cynthia Johnson, Tristram Smith, Naomi Swiezy, Karen Bearss, Carla B Kalvin, Lawrence Scahill

Open access · greenAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Time is of the essence: Age at autism diagnosis, sex assigned at birth, and psychopathology.Autism : the international journal of research and practice · 2024
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Denis G SukhodolskyYale University, USA.ORCID 0000-0002-5401-792X
Luc LecavalierOhio State University, USA.
Cynthia JohnsonCleveland Clinic Lerner College of Medicine, USA.
Tristram SmithUniversity of Rochester Medical Center, USA.
Naomi SwiezyIndiana University, USA.
Karen BearssUniversity of Washington, USA.
Carla B KalvinYale University, USA.
Lawrence ScahillEmory University, USA.
Yale University · USCleveland Clinic Lerner College of Medicine · USEmory University · USIndiana University · USThe Ohio State University · USUniversity of Rochester Medical Center · USUniversity of Washington · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Multimodal Developmental Neurogenetics of Females with ASDR01MH100028 · NIMH · YALE UNIVERSITY · PI Allison Elizabeth Jack, LAUREN KENWORTHY · 2012 to 2026
$37.8M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The University of Rochester's Clinical and Translational Science InstituteUL1TR000042 · NCATS · UNIVERSITY OF ROCHESTER · PI BENNETT, NANCY M, KIEBURTZ, KARL D. · 2012 to 2015
$14.4M
Subnetwork-based Quantitative Imaging Biomarkers for Therapy Assessment in AutismR01NS035193 · NINDS · YALE UNIVERSITY · PI JAMES S DUNCAN, LAWRENCE H. STAIB · 1996 to 2026
$9.2M
Neural Mechanisms of CBT for Anxiety in Children with Autism Spectrum DisorderR01HD083881 · NICHD · YALE UNIVERSITY · PI PELPHREY, KEVIN A, SUKHODOLSKY, DENIS G · 2016 to 2020
$2.8M
Toward Outcome Measurement of Anxiety in Youth with Autism Spectrum DisordersR01MH099021 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2012 to 2015
$2.7M
1/5-Randomized Trial of Parent Training for Young Children with AutismR01MH081148 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2010 to 2014
$1.8M
5/5-Randomized Trial of Parent Training for Young Children with AutismR01MH080965 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSON, CYNTHIA R · 2010 to 2014
$1.2M
2/5-Randomized Trial of Parent Training for Young Children with AutismR01MH081105 · NIMH · OHIO STATE UNIVERSITY · PI LECAVALIER, LUC · 2010 to 2014
$1.1M
NCATS NIH HHS UL1 TR000042NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001863NCRR NIH HHS UL1 RR024139NICHD NIH HHS R01 HD083881NIMH NIH HHS R01 MH080965NIMH NIH HHS R01 MH081105NIMH NIH HHS R01 MH081148NIMH NIH HHS R01 MH099021NIMH NIH HHS R01 MH100028NINDS NIH HHS R01 NS035193
6 · The paper itself

Abstract

Anxiety is a common and impairing problem in children with autism spectrum disorder, but little is known about it in preschool children with autism spectrum disorder. This article reports on the characteristics of anxiety symptoms in young children with autism spectrum disorder using a parent-completed rating scale. One hundred and eighty children (age 3-7 years) participated in a clinical trial of parent training for disruptive behaviors. Anxiety was measured as part of pre-treatment subject characterization with 16 items from the Early Childhood Inventory, a parent-completed scale on child psychiatric symptoms. Parents also completed other measures of behavioral problems. Sixty-seven percent of children were rated by their parents as having two or more clinically significant symptoms of anxiety. There were no differences in the Early Childhood Inventory anxiety severity scores of children with IQ < 70 and those with ⩾70. Higher levels of anxiety were associated with severity of oppositional defiant behavior and social disability. Anxiety symptoms are common in preschoolers with autism spectrum disorder. These findings are consistent with earlier work in school-age children with autism spectrum disorder. There were no differences in anxiety between children with IQ below 70 and those with IQ of 70 and above. Social withdrawal and oppositional behavior were associated with anxiety in young children with autism spectrum disorder.

Indexed as

AnxietyAnxiety DisordersAttention Deficit and Disruptive Behavior DisordersAutism Spectrum DisorderChildChild, PreschoolFemaleHumansMaleParentsProblem Behavioranxietyautismautism spectrum disorderearly childhood inventoryyoung children

Identifiers

PMID31390873
PMCPMC6982590
OpenAlexW2967021082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.