ArticleDiagnostics (Basel, Switzerland)2019
Measurement of Oral Epithelial Thickness by Optical Coherence Tomography.
Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Article
- Epithelial thickness as a new predictor of recurrence in oral leukoplakia after photodynamic therapy: a retrospective cohort study.BMC oral health · 2026Article
- Surgeons' Perceptions on the Utility of a Conceptual Novel Force Sensor at the Surgeon-Tool Interface: Formative Interview Study.JMIR formative research · 2026Article
- Secreted factors ofApplied and environmental microbiology · 2026Article
- Novel liquid-based approaches for transmucosal drug delivery.Acta pharmaceutica Sinica. B · 2026Review
- Contrasting biological responses of gingival fibroblasts and keratinocyte to blue and violet light irradiation: implications for photobiomodulation use in the therapeutic management of periodontal disease.Lasers in medical science · 2026Article
- Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor-Microenvironment-on-a-Chip.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Impact of Optical Coherence Tomography (OCT) for Periodontitis Diagnostics: Current Overview and Advances.Dentistry journal · 2025Review
- Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: Preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy.Biophotonics discovery · 2025Article
- Assessment ofMolecular pharmaceutics · 2025Article
- Safety of oral mucosal punch biopsy and other oral biospecimen collections in clinical research.Oral surgery, oral medicine, oral pathology and oral radiology · 2025Article
- Titania nanotubes with aminated reduced graphene oxide as efficient photocatalysts for antibacterial application under visible light.Scientific reports · 2025Article
- Enhancing Oral Cancer Detection: A Systematic Review of the Diagnostic Accuracy and Future Integration of Optical Coherence Tomography with Artificial Intelligence.Journal of clinical medicine · 2024Review
- Hyperspectral imaging with deep learning for quantification of tissue hemoglobin, melanin, and scattering.Journal of biomedical optics · 2024Article
- Imaging Biomarkers of Oral Dysplasia and Carcinoma Measured with In Vivo Endoscopic Optical Coherence Tomography.Cancers · 2024Article
- Three-Dimension Epithelial Segmentation in Optical Coherence Tomography of the Oral Cavity Using Deep Learning.Cancers · 2024Article
- Biological Response of the Peri-Implant Mucosa to Different Definitive Implant Rehabilitation Materials.Polymers · 2024Article
- Oral mucosa - an examination map for confocal laser endomicroscopy within the oral cavity: an experimental clinical study.Clinical oral investigations · 2024Article
- Oral mucosal vaccination using integrated fiber microneedles.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- Quantitative assessment of the oral microvasculature using optical coherence tomography angiography.Frontiers in bioengineering and biotechnology · 2024Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical coherence tomography (OCT) is a real-time, in-situ, non-invasive imaging device that is able to perform a cross-sectional evaluation of tissue microstructure based on the specific intensity of back-scattered and reflected light. The aim of the present study was to define normal values of epithelial thickness within the oral cavity. OCT measurements of epithelial thickness were performed in 28 healthy patients at six different locations within the oral cavity. Image analysis was performed using Image J 1.52 software. The healthy epithelium has a mean thickness of 335.59 ± 150.73 µm. According to its location within the oral cavity, the epithelium showed highest values in the region of the buccal mucosa (659.79 µm) and the thinnest one was observed in the mouth's floor (100.07 µm). OCT has been shown to be useful for the evaluation of oral mucosa in vivo and in real time. Our study provides reference values for the epithelial thickness of multiple sites within the oral cavity. Knowledge of the thickness values of healthy mucosa is, therefore, of fundamental importance.
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