ReviewNutrients2019
Xylitol's Health Benefits beyond Dental Health: A Comprehensive Review.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05618483 (Clinical Efficacy of Xylitol Based Nasal Spray for the Treatment of Mild COVID-19 Infection), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Efficacy of Xylitol Based Nasal Spray for the Treatment of Mild COVID-19 Infection
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Effects of Xylitol-laced Sweets on the Accumulation of Dental Plaque : A Systematic Review and Meta-Analysis.International dental journal · 2025Pooled it
- Washing Illness Away: A Systematic Review of the Impact of Nasal Irrigation and Spray on COVID-19.The Laryngoscope · 2025Pooled it
- Effects of sugar-free polyol chewing gums on gingival inflammation: a systematic review.Clinical oral investigations · 2022Pooled it
- Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Fecal Microbiome and Host Metabolism.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Trial
- Frailty-Preventing Effect of an Intervention Program Using a Novel Complete Nutritional "COMB-FP Meal": A Pilot Randomized Control Trial.Nutrients · 2023Trial
- Elucidation of sugar metabolic profiles and transcriptional regulatory networks during the developmental stages of sweet corn kernels.iScience · 2026Article
- Remineralizing and Antimicrobial Effects of a Chitosan-Xylitol Hydrogel on Dental Enamel: An In Vitro Study.Gels (Basel, Switzerland) · 2026Article
- In Vitro Inhibition of Pathogens by Polyols: Optical Density-Based Screening and Implications for the Oral-Systemic Axis.Microorganisms · 2026Article
- Xylitol Modification of Electrospun Polymer Scaffolds: Impact on Physicochemical and Antibacterial Properties.Polymers · 2025Article
- Exploring the Phytochemical and Physical Stability of Phycocyanin, Anthocyanins, and Betacyanin in a Cheesecake Product.Molecular nutrition & food research · 2025Article
- Potential Effects of Low-Calorie Sweeteners on Human Health.Nutrients · 2025Review
- Using gut microbiota and non-targeted metabolomics techniques to study the effect of xylitol on alleviating DSS-induced inflammatory bowel disease in mice.BMC immunology · 2025Article
- Cooking for disability: a pilot study on nutritional interventions for mental health support in adults with autism spectrum disorder.Frontiers in psychiatry · 2025Article
- Food sweeteners: Angels or clowns for human health?Current research in food science · 2025Review
- Article
- Real-time acid production and extracellular matrix formation in mature biofilms of threeBiofilm · 2024Article
- Intestinal homeostasis disrupted by Periodontitis exacerbates Alzheimer's Disease in APP/PS1 mice.Journal of neuroinflammation · 2024Article
- Altered sterol composition mediates multiple tolerance of Kluyveromyces marxianus for xylitol production.Microbial cell factories · 2024Article
- Salivary Transcriptome and Mitochondrial Analysis of Autism Spectrum Disorder Children Compared to Healthy Controls.NeuroSci · 2024Article
- Whole-Genome Deep Sequencing of the Healthy Adult Nasal Microbiome.Microorganisms · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xylitol has been widely documented to have dental health benefits, such as reducing the risk for dental caries. Here we report on other health benefits that have been investigated for xylitol. In skin, xylitol has been reported to improve barrier function and suppress the growth of potential skin pathogens. As a non-digestible carbohydrate, xylitol enters the colon where it is fermented by members of the colonic microbiota; species of the genus
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.