Evidence map›Paper›PMID 31390651›Full record

ArticlePediatric research2019

Very preterm neonates receiving "aggressive" nutrition and early nCPAP had similar long-term respiratory outcomes as term neonates.

Polytimi Panagiotounakou, Rozeta Sokou, Eleni Gounari, Aikaterini Konstantinidi, George Antonogeorgos, Ioanna N Grivea, Zoi Daniil, Konstantinos I Gourgouliannis, Antonios Gounaris

Open access · hybridAbstract read
In one paragraph

Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Impaired lung function and associated risk factors in children born prematurely: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Polytimi PanagiotounakouNICU General Hospital "Agios Panteleimon", Piraeus, Greece.
Rozeta SokouNICU General Hospital "Agios Panteleimon", Piraeus, Greece.
Eleni GounariRoyal Alexandra Children's Hospital, Brighton, UK.
Aikaterini KonstantinidiNICU General Hospital "Agios Panteleimon", Piraeus, Greece.
George AntonogeorgosNICU General Hospital "Agios Panteleimon", Piraeus, Greece.
Ioanna N GriveaNICU, University Hospital of Larissa, Larissa, Greece.
Zoi DaniilRespiratory Medicine Department, University of Thessaly School of Medicine, University Hospital of Larissa, Larissa, Greece.
Konstantinos I GourgouliannisRespiratory Medicine Department, University of Thessaly School of Medicine, University Hospital of Larissa, Larissa, Greece.
Antonios GounarisNICU, University Hospital of Larissa, Larissa, Greece. angounaris@med.uth.gr.
General Hospital of Nikea · GRUniversity Hospital of Larissa · GRRoyal Alexandra Children's Hospital · GBUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backroundThe impact of the consistent implementation of "aggressive" nutrition by means of intensive early neonatal nutritional support up to 40-44 weeks postmenstrual age and the use of nasal continuous positive airway pressure (nCPAP) within the first hour of life on the respiratory function of very premature neonates (VPN) at school age is unclear.

methodRespiratory function was evaluated in 108 VPN and 70 term controls. Growth, frequency of lower respiratory tract infections, re-hospitalization, and spirometry were recorded up to 8-10 years of age. Comparison was carried out between the two study groups.

resultsThere was no significant difference in forced expiratory volume in 1 s and forced vital capacity at 8 years of age, and also in lower respiratory tract infections and re-hospitalization due to them, up to 8 years of age between preterm and term neonates. No significant difference was found in spirometry measurements neither between premature neonates with and without BPD nor between the two subgroups of preterms and term neonates.

conclusion"Aggressive" nutrition, persistent nCPAP use, and their impact on early postnatal growth probably positively affect the respiratory function of our study population. These very encouraging results need to be confirmed by larger studies.

Indexed as

Infant, Extremely PrematureChildContinuous Positive Airway PressureDiet TherapyFemaleHumansInfant, NewbornMaleNutritional StatusRespiratory Function Tests

Identifiers

PMID31390651
PMCPMC6887846
OpenAlexW2965278628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.