ArticleRevista de saude publica2019
Trend analysis of leprosy indicators in a hyperendemic Brazilian state, 2001-2015.
Article in Revista de saude publica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Measuring endemicity and burden of leprosy across countries and regions: A systematic review and Delphi survey.PLoS neglected tropical diseases · 2021Pooled it
- Geospatial inequalities in severe leprosy disability in Pernambuco before and during COVID-19.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases · 2026Article
- Temporal trend and factors associated with physical disability due to leprosyl: a time series study, Brazil, 2014-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Socioeconomic determinants of the leprosy risk in Yunnan Province, China: a county-level spatiotemporal study.Frontiers in public health · 2025Article
- Leprosy elimination phase in Alagoas, 2001-2022: an ecological study.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Quality of healthcare services to reduce leprosy in Brazil: a trend analysis from 2001 to 2020.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Article
- Leprosy prevalence spatial distribution and trend in a health region in Northeast Brazil, 2008-2017: an ecological study.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
- Serum Levels of Ficolin-3 and Mannose-Binding Lectin in Patients with Leprosy and Their Family Contacts in a Hyperendemic Region in Northeastern Brazil.Tropical medicine and infectious disease · 2022Article
- Trends and forecasts of leprosy for a hyperendemic city from Brazil's northeast: Evidence from an eleven-year time-series analysis.PloS one · 2020Article
- Leprosy morbidity and mortality in Brazil: 2008-2018.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
- Hanseniasis in the municipality of Western Amazon (Acre, Brazil): are we far from the goal of the World Health Organization?: Hansen and Western Amazon.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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8 authors.
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Abstract
objectiveTo analyze the temporal trend of leprosy indicators in a hyperendemic state of Brazil, from 2001-2015.
methodsThis is a time-series study of leprosy indicators in the state of Maranhão, Northeastern region of Brazil. The study used data from the Brazilian National System of Reportable Diseases, for the period between 2001 and 2015. The following indicators were evaluated: (i) detection coefficient in the general population; (ii) detection coefficient in people under 15 years old; (iii) rate of cases with grade 2 physical disability in the diagnosis; (iv) rate of examined contacts, and (v) proportion of healing . The Prais-Winsten regression model was used for trend analysis. Analyses were performed for the state and by each health region.
results77,697 leprosy cases were analyzed in the general population and 7,599 in individuals under 15 years old. The detection coefficient in the general population ranged from 80.7/100 thousand inhabitants in 2001 to 51.2/100 thousand inhabitants in 2015. The coefficient in the general population presented a downward trend (annual percentage variation [APV] = -2.98; 95%CI -4.15- -1.79). For the population under 15 years old, the rate was 24.9/100 thousand inhabitants in 2001, and 19.9/100 thousand inhabitants in 2015, with downward trend (APV = -3.07; 95%CI -4.95- -1.15). It was observed upward trend in rate of contacts examined (APV = 2.35; 95%CI 0.58-4.15) and rate of cases with grade 2 disability (APV = 2.19; 95%CI 0.23-4.19). Stationary trend was observed in the proportion of healing (APV = -0.10; 95%CI -0.50-0.30). Regional differences were found in the performance of the indicators.
conclusionsA downward trend for the detection coefficients in the general population and in individuals under 15 years old was found in Maranhão. Despite this result, the rates are still very high, demanding efforts from all spheres of public administration and health professionals to reduce the burden of the disease in the state.
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