Evidence map›Paper›PMID 31390226›Full record

ArticleAmerican journal of physiology. Cell physiology2019

Transgenic expression of carbonic anhydrase III in cardiac muscle demonstrates a mechanism to tolerate acidosis.

Han-Zhong Feng, J-P Jin

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Cardiovascular Biomarkers: Tools for Precision Diagnosis and Prognosis.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Emerging biomarkers for the detection of cardiovascular diseases.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Review
  7. The therapeutic importance of acid-base balance.Biochemical pharmacology · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Han-Zhong FengDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.
J-P JinDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.
Wayne State University · US

Funding

Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
Targeting Troponin T Regulation to Sustain Cardiac Function in Heart FailureR01HL138007 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2018 to 2026
$2.4M
NHLBI NIH HHS R01 HL127691NHLBI NIH HHS R01 HL138007
6 · The paper itself

Abstract

Carbonic anhydrase III (CAIII) is abundant in liver, adipocytes, and skeletal muscles, but not heart. A cytosolic enzyme that catalyzes conversions between CO

Indexed as

Gene Expression Regulation, EnzymologicAcidosisAnimalsCarbonic Anhydrase IIIFemaleMaleMiceMice, Inbred C57BLMice, TransgenicMyocardiumCarbonic Anhydrase IIIacidosiscarbonic anhydraseex vivo working heartheartmuscle

Identifiers

PMID31390226
PMCPMC6879876
OpenAlexW2966591001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.