Evidence map›Paper›PMID 31390137›Full record

ArticleJournal of applied clinical medical physics2019

Noise reduction in dual-energy computed tomography virtual monoenergetic imaging.

Chi-Kuang Liu, Hsuan-Ming Huang

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Dual-energy CT-based virtual monoenergetic imaging via unsupervised learning.Physical and engineering sciences in medicine · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chi-Kuang LiuDepartment of Medical Imaging, Changhua Christian Hospital, Changhua City, Taiwan.
Hsuan-Ming HuangInstitute of Medical Device and Imaging, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVirtual monoenergetic images (VMIs) derived from dual-energy computed tomography (DECT) have been explored for several clinical applications in recent years. However, VMIs at low and high keVs have high levels of noise. The aim of this study was to reduce image noise in VMIs by using a two-step noise reduction technique.

methodsVMI was first denoised using a modified highly constrained backprojection (HYPR) method. After the first-step denoising, a general-threshold filtering method was performed. Two sets of anthropomorphic phantoms were scanned with a clinical dual-source DECT system. DECT data (80/140Sn kV) were reconstructed as VMI series at 12 different energy levels (range, 40-150 keV, interval, 10 keV). For comparison, the averaged VMIs obtained from 10 repeated DECT scans were used as the reference standard. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and root-mean-square error (RMSE) were used to evaluate the quality of VMIs.

resultsCompared to the original HYPR method, the proposed two-step image denoising method could provide better performance in terms of SNR, CNR, and RMSE. In addition, the proposed method could achieve effective noise reduction while preserving edges and small structures, especially for low-keV VMIs.

conclusionThe proposed two-step image denoising method is a feasible method for reducing noise in VMIs obtained from a clinical DECT scanner. The proposed method can also reduce edge blurring and the loss of intensity in small lesions.

Indexed as

AlgorithmsPhantoms, ImagingSignal-To-Noise RatioBrainHumansRadiographic Image Interpretation, Computer-AssistedRadiography, Dual-Energy Scanned ProjectionTomography, X-Ray Computeddual-energy computed tomographynoise reductionvirtual monoenergetic images

Identifiers

PMID31390137
PMCPMC6753738

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.