Evidence map›Paper›PMID 31389969›Full record

ArticleJournal of materials chemistry. B2019

A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging.

Hao Liu, Rebecca T Marquez, Xiaoqing Wu, Ke Li, Shweta Vadlamani, Song Li, Ya Wang, Liang Xu, Daocheng Wu

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Gastric floating tablet improves the bioavailability and reduces the hypokalemia effect of gossypolSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao LiuDepartment of Pharmaceutics, School of Pharmacy, Southwest Medical University, Luzhou City, Sichuan Province 646000, P. R. China.
Rebecca T Marquez
Xiaoqing Wu
Ke Li
Shweta Vadlamani
Song Li
Ya Wang
Liang Xu
Daocheng Wu

Funding

Molecular cancer therapy targeting HuR-ARE interactionR01CA191785 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY, XU, LIANG · 2015 to 2019
$2.1M
Small molecules modulating RNA-binding protein Msi1R01CA178831 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI NEUFELD, KRISTI L, XU, LIANG · 2014 to 2016
$1.3M
NCI NIH HHS R01 CA178831NCI NIH HHS R01 CA191785
6 · The paper itself

Abstract

We developed a novel evaluation method for tumor-targeting characteristics of nanomedicines, average tumor-targeting index (average TTI) and "area under the tumor-targeting index-time curve" (AUTC) were established as the indicators for tumor targeting of nanomedicines based on NIR fluorescence imaging, which helps real-time monitoring of targeting ability and tumor changes in vivo without culling animals.

Indexed as

AnimalsAntineoplastic AgentsCarbocyaninesCell Line, TumorDrug CarriersFemaleFluorescent DyesGossypolHumansHyaluronic AcidMicellesMice, SCIDNanoparticlesNeoplasmsOptical ImagingPolyethyleneimine1,1'-dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanineAntineoplastic AgentsCarbocyaninesDrug CarriersFluorescent DyesGossypolHyaluronic AcidMicellesPolyethyleneimine

Identifiers

PMID31389969
PMCPMC6686867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.