Evidence map›Paper›PMID 31389777›Full record

ReviewPhysiology (Bethesda, Md.)2019

Walk the Line: The Role of Ubiquitin in Regulating Transcription in Myocytes.

Vidyani Suryadevara, Monte S Willis

Open access · bronzeAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vidyani SuryadevaraDepartment of Pathology & Laboratory Medicine, Indianapolis, Indiana.
Monte S WillisDepartment of Pathology & Laboratory Medicine, Indianapolis, Indiana.ORCID 0000-0002-0769-5816
Indiana University School of Medicine

Funding

Myocyte specific regulation of metabolism and the response to biomechanical forceR01HL104129 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIS, MONTE S · 2010 to 2018
$3.3M
NHLBI NIH HHS R01 HL104129
6 · The paper itself

Abstract

The ubiquitin-proteasome offers novel targets for potential therapies with their specific activities and tissue localization. Recently, the expansion of our understanding of how ubiquitin ligases (E3s) specifically regulate transcription has demonstrated their roles in skeletal muscle, complementing their roles in protein quality control and protein degradation. This review focuses on skeletal muscle E3s that regulate transcription factors critical to myogenesis and the maintenance of skeletal muscle wasting diseases.

Indexed as

AnimalsHumansMuscle CellsMuscle, SkeletalProteasome Endopeptidase ComplexTranscription FactorsTranscription, GeneticUbiquitinUbiquitin-Protein LigasesProteasome Endopeptidase ComplexTranscription FactorsUbiquitinUbiquitin-Protein Ligasesatrophydifferentiationskeletal muscletranscription factorsubiquitin ligase

Identifiers

PMID31389777
PMCPMC6863375
OpenAlexW2965118610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.