Evidence map›Paper›PMID 31389710›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2019

NIR-Light-Driven Generation of Reactive Oxygen Species Using Ru(II)-Decorated Lipid-Encapsulated Upconverting Nanoparticles.

Michael S Meijer, Victorio Saez Talens, Michiel F Hilbers, Roxanne E Kieltyka, Albert M Brouwer, Marta M Natile, Sylvestre Bonnet

Open access · hybridAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

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  11. NIR-Absorbing RuChembiochem : a European journal of chemical biology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Michael S MeijerLeiden Institute of Chemistry , Leiden University , P.O. Box 9502, 2300 RA Leiden , The Netherlands.ORCID 0000-0003-0877-2374
Victorio Saez TalensLeiden Institute of Chemistry , Leiden University , P.O. Box 9502, 2300 RA Leiden , The Netherlands.
Michiel F HilbersVan't Hoff Institute for Molecular Sciences , University of Amsterdam , P.O. Box 94157, 1090 GD Amsterdam , The Netherlands.
Roxanne E KieltykaLeiden Institute of Chemistry , Leiden University , P.O. Box 9502, 2300 RA Leiden , The Netherlands.ORCID 0000-0001-9152-1810
Albert M BrouwerVan't Hoff Institute for Molecular Sciences , University of Amsterdam , P.O. Box 94157, 1090 GD Amsterdam , The Netherlands.ORCID 0000-0002-1731-3869
Marta M NatileInstitute of Condensed Matter Chemistry and Technologies for Energy (ICMATE), National Research Council (CNR), c/o Department of Chemical Sciences , University of Padova , via F. Marzolo 1 , 35131 Padova , Italy.ORCID 0000-0001-5591-2670
Sylvestre BonnetLeiden Institute of Chemistry , Leiden University , P.O. Box 9502, 2300 RA Leiden , The Netherlands.ORCID 0000-0002-5810-3657
Leiden University · NLUniversity of Amsterdam · NLInstitute of Condensed Matter Chemistry and Technologies for Energy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological application of ruthenium anticancer prodrugs for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) is restricted by the need to use poorly penetrating high-energy photons for their activation, i.e., typically blue or green light. Upconverting nanoparticles (UCNPs), which produce high-energy light under near-infrared (NIR) excitation, may solve this issue, provided that the coupling between the UCNP surface and the Ru prodrug is optimized to produce stable nanoconjugates with efficient energy transfer from the UCNP to the ruthenium complex. Herein, we report on the synthesis and photochemistry of the two structurally related ruthenium(II) polypyridyl complexes [Ru(bpy)

Identifiers

PMID31389710
PMCPMC6753655
OpenAlexW2964708031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.