Evidence map›Paper›PMID 31389254›Full record

ArticleClinical toxicology (Philadelphia, Pa.)2020

Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning.

Adrian Thompson, Michael Dunn, Robert D Jefferson, Kosala Dissanayake, Frances Reed, Rachael Gregson, Stephen Greenhalgh, R Eddie Clutton, Peter G Blain, Simon Hl Thomas and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical toxicology (Philadelphia, Pa.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Adrian ThompsonDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Michael DunnMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK.
Robert D JeffersonMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK.
Kosala DissanayakeDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Frances ReedWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Rachael GregsonWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Stephen GreenhalghWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
R Eddie CluttonWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Peter G BlainMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK.
Simon Hl ThomasMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK.
Michael EddlestonDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-6857-3441
Newcastle University · GBRoslin Institute · GBUniversity of Edinburgh · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntidotesChelating AgentsCyanidesDisease Models, AnimalDose-Response Relationship, DrugEdetic AcidHydroxocobalaminMalePre-Exposure ProphylaxisSwineSwine, MiniatureAntidotesChelating Agentscobalt-ethylenediamine tetraacetic acid chelateCyanidesEdetic AcidHydroxocobalaminantidotesCyanideefficacy

Identifiers

PMID31389254
PMCPMC7034532
OpenAlexW2966536607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.