Evidence map›Paper›PMID 31389193›Full record

ArticleAdvanced healthcare materials2019

Cell Membrane-Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme.

Christos Tapeinos, Francesca Tomatis, Matteo Battaglini, Aitor Larrañaga, Attilio Marino, Iker Aguirrezabal Telleria, Makis Angelakeris, Doriana Debellis, Filippo Drago, Francesca Brero and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Advanced healthcare materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Spatiotemporal cancer controlNanomedicine (London, England) · 2026
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  7. The blood-brain barrier: structure, regulation, and drug delivery.Signal transduction and targeted therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Christos TapeinosSmart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera, Italy.ORCID 0000-0001-8192-6750
Francesca TomatisDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129, Torino, Italy.
Matteo BattagliniSmart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera, Italy.
Aitor LarrañagaDepartment of Mining-Metallurgy Engineering and Materials Science & POLYMAT, University of the Basque Country, 48013, Bilbao, Spain.
Attilio MarinoSmart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera, Italy.
Iker Aguirrezabal TelleriaDepartment of Chemical and Environmental Engineering, Engineering School of the University of the Basque Country (UPV/EHU), 48013, Bilbao, Spain.
Makis AngelakerisDepartment of Physics, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
Doriana DebellisElectron Microscopy Facility, Istituto Italiano di Tecnologia, 16163, Genova, Italy.
Filippo DragoNanochemistry Department, Istituto Italiano di Tecnologia, 16163, Genova, Italy.
Francesca BreroDepartment of Physics and INSTM, Università degli Studi di Pavia, 27100, Pavia, Italy.
Paolo ArosioDepartment of Physics and INSTM, Università degli Studi di Milano, 20133, Milano, Italy.
Alessandro LascialfariDepartment of Physics and INSTM, Università degli Studi di Milano, 20133, Milano, Italy.
Andrea PetrettoCore Facilities-Clinical Proteomics and Metabolomics Laboratory, IRCCS Istituto Giannina Gaslini, 16147, Genova, Italy.
Edoardo SinibaldiCenter for Micro-BioRobotics, Istituto Italiano di Tecnologia, 56025, Pontedera, Italy.
Gianni CiofaniSmart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera, Italy.
Italian Institute of Technology · ITPolitecnico di Torino · ITUniversity of Milan · ITUniversity of the Basque Country · ESAristotle University of Thessaloniki · GRIstituto Giannina Gaslini · ITScuola Superiore Sant'Anna · ITUniversity of Pavia · IT

Funding

COST Action EURELAX CA15209COST Action MyWAVE CA17115European Research Council 709613
6 · The paper itself

Abstract

In this study, hybrid nanocubes composed of magnetite (Fe

Indexed as

TemperatureTheranostic NanomedicineApoptosisBlood-Brain BarrierCell Line, TumorCell MembraneDrug LiberationDynamic Light ScatteringEndocytosisFluorescenceGlioblastomaHumansHyperthermia, InducedMagnetite NanoparticlesOxygenProtein CoronaMagnetite NanoparticlesOxygenProtein CoronaReactive Oxygen Speciescell membrane-coated nanocubesglioblastomahomotypic targetingmagnetic hyperthermiatheranostics

Identifiers

PMID31389193
PMCPMC6754263
OpenAlexW2966870853

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.