Evidence map›Paper›PMID 31389059›Full record

ReviewBritish journal of clinical pharmacology2019

Why is the therapeutic effect of acute antimigraine drugs delayed? A review of controlled trials and hypotheses about the delay of effect.

Peer Tfelt-Hansen, Karl Messlinger

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Peer Tfelt-HansenDanish Headache Center, Department of Neurology, Rigshospitalet-Glostrup Hospital, University of Copenhagen, Glostrup, Denmark.
Karl MesslingerInstitute of Physiology and Pathophysiology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0002-8099-3860
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In randomised controlled trials (RCTs) of oral drug treatment of migraine attacks, efficacy is evaluated after 2 hours. The effect of oral naratriptan 2.5 mg with a maximum blood concentration (T

Indexed as

Randomized Controlled Trials as TopicAdministration, OralAnti-Inflammatory Agents, Non-SteroidalArteriesCalcitonin Gene-Related Peptide Receptor AntagonistsHumansMigraine DisordersNociceptionSerotonin 5-HT1 Receptor AgonistsThalamusTime FactorsTreatment OutcomeTrigeminal GanglionVasoconstrictionAnti-Inflammatory Agents, Non-SteroidalCalcitonin Gene-Related Peptide Receptor AntagonistsSerotonin 5-HT1 Receptor Agonistsacute antimigraine drugeffect delayNSAIDtime-effect curvetriptan

Identifiers

PMID31389059
PMCPMC6848898
OpenAlexW2965059885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.