Evidence map›Paper›PMID 31388967›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Assessment of motion correction in dynamic rubidium-82 cardiac PET with and without frame-by-frame adjustment of attenuation maps for calculation of myocardial blood flow.

Ian S Armstrong, Matthew J Memmott, Kimberley J Saint, Antoine Saillant, Charles Hayden, Parthiban Arumugam

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Detection and correction of patient motion in dynamicJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. Automated dynamic motion correction improves repeatability and reproducibility of myocardial blood flow quantification with rubidium-82 PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. The prevalence of image degradation due to motion in rest-stress rubidium-82 imaging on a SiPM PET-CT system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. CardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. A preliminary evaluation of a high temporal resolution data-driven motion correction algorithm for rubidium-82 on a SiPM PET-CT system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Article
  8. Optimizing accuracy and precision with motion correction of PET myocardial blood flow measurements.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  9. Myocardial blood flow: Is motion correction necessary?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  10. Deriving myocardial blood flow reserve from perfusion datasets: Dream or reality?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  11. Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Review
  12. 3D PET/CTEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ian S ArmstrongNuclear Medicine, Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK. Ian.Armstrong@mft.nhs.uk.
Matthew J MemmottNuclear Medicine, Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK.
Kimberley J SaintNuclear Medicine, Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK.
Antoine SaillantSiemens Medical Solutions USA, Inc, Molecular Imaging, Knoxville, TN, USA.
Charles HaydenSiemens Medical Solutions USA, Inc, Molecular Imaging, Knoxville, TN, USA.
Parthiban ArumugamNuclear Medicine, Manchester University NHS Foundation Trust, Oxford Road, Manchester, UK.
Manchester University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient motion during pharmacological stressing can have substantial impact on myocardial blood flow (MBF) estimated from dynamic PET. This work evaluated a motion correction algorithm with and without adjustment of the PET attenuation map.

methodsFrame-by-frame motion correction was performed by three users on 30 rubidium-82 studies. Data were divided equally into three groups of motion severity [mild (M1), moderate (M2) and severe (M3)]. MBF data were compared for non-motion corrected (NC), motion-corrected-only (MC) and with adjustment of the attenuation map (MCAC). Percentage differences of MBF were calculated in the coronary territories and 17-segment polar plots. Polar plots of spill-over were also generated from the data.

resultsMedian differences of 23% were seen in the RCA and 18% for the LAD in the M3 category for MC vs NC images. Differences for MCAC vs MC images were considerably smaller and typically < 10%. Spill-over plots for MC and MCAC were notably more uniform compared with NC images.

conclusionMotion correction for dynamic rubidium data is desirable for future MBF software updates. Adjustment of the PET attenuation map results in only marginal differences and therefore is unlikely to be an essential requirement. Assessing the uniformity of spill-over plots is a useful visual aid for verifying motion correction techniques.

Indexed as

Image Processing, Computer-AssistedMotionMyocardial Perfusion ImagingPositron-Emission TomographyCoronary Artery DiseaseCoronary CirculationHumansReproducibility of ResultsRetrospective StudiesRubidium RadioisotopesRubidium-82Rubidium RadioisotopesCADimage analysisimage reconstructionmyocardial blood flowPET

Identifiers

PMID31388967
OpenAlexW2965955403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.