ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2020
Effects of a functional food supplemented with probiotics on biological factors related to dental caries in children: a pilot study.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Effect of probiotic interventions on oral health in children: a systematic review.Frontiers in dental medicine · 2026Pooled it
- Unlocking the potential of probiotic administration in caries management: a systematic review.BMC oral health · 2024Pooled it
- Effect of a Short-Term Intervention withInternational journal of environmental research and public health · 2022Trial
- Effect of Lactobacillus brevis CD2 containing lozenges and plaque pH and cariogenic bacteria in diabetic children: a randomised clinical trial.Clinical oral investigations · 2021Trial
- The potential of bioactive compounds in functional foods for caries disease prevention an updated scoping review of clinical studies.Clinical oral investigations · 2026Article
- Review
- Remineralization of artificial caries lesions using casein phosphopeptide-amorphous calcium phosphate containing probiotic lozenge: an in vitro study.BMC oral health · 2025Article
- The strategic role of biotics in dental caries prevention: A scoping review.Food science & nutrition · 2024Article
- Altered salivary microbiota associated with high-sugar beverage consumption.Scientific reports · 2024Article
- Review
- Can acid produced from probiotic bacteria alter the surface roughness, microhardness, and elemental composition of enamel? An in vitro study.Odontology · 2023Article
- A review on the immunomodulatory properties of functional nutraceuticals as dietary interventions for children to combat COVID-19 related infections.Food production, processing and nutrition · 2023Review
- A comprehensive review of the application of probiotics and postbiotics in oral health.Frontiers in cellular and infection microbiology · 2023Review
- Teff-Based Probiotic Functional Beverage Fermented withFoods (Basel, Switzerland) · 2021Article
- Marine Bioactive Compounds as Nutraceutical and Functional Food Ingredients for Potential Oral Health.Frontiers in nutrition · 2021Review
- A Review of the Role of Probiotic Supplementation in Dental Caries.Probiotics and antimicrobial proteins · 2020Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe aim of this study was to evaluate the effects of a functional food supplemented with probiotics on biological factors related to dental caries in children aged 3-5 years.
methodsA repeated measures pilot study was conducted with children who have consumed a commercial milk containing two lactic acid bacteria as probiotics (WP milk) for a period of 3 months and another period of 3 months consuming a milk without probiotics (NP milk). Salivary pH, plaque index, pH variation before and after a sugar rinse, quantification of Streptococcus mutans in saliva and demineralisation of the carious lesions were determined at the beginning and at the end of both milk ingestion periods.
resultsRegarding WP milk, a non-significant decrease in terms of the concentration of S. mutans and pH variation (p > 0.05), a significant decrease (i.e. acidification) in salivary pH (p < 0.01) and a remineralisation of 39.4% of the caries were found. On the other hand, for NP milk, a non-significant increase in terms of the concentration of S. mutans, pH variation, salivary pH (p > 0.05) and a remineralisation of 64.2% were found.
conclusionsLactic acid probiotics can contribute to the decrease in the number of cariogenic microorganisms. However, the appropriate selection of the bacteria type with regard to its acidogenicity is fundamental to avoid the generation of an effect contrary to that expected, e.g. a significant decrease in salivary pH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.